Thiagarajan Venkataraman
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Explore the profile of Thiagarajan Venkataraman including associated specialties, affiliations and a list of published articles.
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19
Citations
1072
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Recent Articles
1.
Liebhoff A, Venkataraman T, Morgenlander W, Na M, Kula T, Waugh K, et al.
Nat Commun
. 2024 Feb;
15(1):1577.
PMID: 38383452
We investigate a relatively underexplored component of the gut-immune axis by profiling the antibody response to gut phages using Phage Immunoprecipitation Sequencing (PhIP-Seq). To cover large antigenic spaces, we develop...
2.
Liechti T, Van Gassen S, Beddall M, Ballard R, Iftikhar Y, Du R, et al.
Cell Rep Methods
. 2023 Oct;
3(10):100619.
PMID: 37883924
High-dimensional flow cytometry is the gold standard to study the human immune system in large cohorts. However, large sample sizes increase inter-experimental variation because of technical and experimental inaccuracies introduced...
3.
Liebhoff A, Venkataraman T, Morgenlander W, Na M, Kula T, Waugh K, et al.
bioRxiv
. 2023 Aug;
PMID: 37577562
We investigated a relatively underexplored component of the gut-immune axis by profiling the antibody response to gut phages using Phage Immunoprecipitation Sequencing (PhIP-Seq). To enhance this approach, we developed Dolphyn,...
4.
Comprehensive profiling of antibody responses to the human anellome using programmable phage display
Venkataraman T, Swaminathan H, Arze C, Jacobo S, Bhattacharyya A, David T, et al.
Cell Rep
. 2022 Dec;
41(12):111754.
PMID: 36543141
Anelloviruses represent a major constituent of the commensal human virome; however, little is known about their immunobiology. Here, we present "AnelloScan," a T7 phage library representing the open reading frame...
5.
Rasquinha M, Lasrado N, Petro-Turnquist E, Weaver E, Venkataraman T, Anderson D, et al.
Biology (Basel)
. 2022 Sep;
11(7).
PMID: 36101433
Enteroviruses such as group B coxsackieviruses (CVB) are commonly suspected as causes of myocarditis that can lead to dilated cardiomyopathy (DCM), and the mouse model of CVB3 myocarditis is routinely...
6.
Angkeow J, Monaco D, Chen A, Venkataraman T, Jayaraman S, Valencia C, et al.
Immunity
. 2022 Jun;
55(6):1051-1066.e4.
PMID: 35649416
Microbial exposures are crucial environmental factors that impact healthspan by sculpting the immune system and microbiota. Antibody profiling via Phage ImmunoPrecipitation Sequencing (PhIP-Seq) provides a high-throughput, cost-effective approach for detecting...
7.
Venkataraman T, Valencia C, Mangino M, Morgenlander W, Clipman S, Liechti T, et al.
Immunity
. 2022 Jan;
55(1):174-184.e5.
PMID: 35021055
Human immune responses to viral infections are highly variable, but the genetic factors that contribute to this variability are not well characterized. We used VirScan, a high-throughput epitope scanning technology,...
8.
Roman-Melendez G, Venkataraman T, Monaco D, Larman H
Cell Syst
. 2020 Oct;
11(4):375-381.e4.
PMID: 33099407
Endopeptidases catalyze the internal cleavage of proteins, playing pivotal roles in protein turnover, substrate maturation, and the activation of signaling cascades. A broad range of biological functions in health and...
9.
Venkataraman T, Coleman C, Frieman M
J Virol
. 2017 Apr;
91(12).
PMID: 28404843
Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly pathogenic respiratory virus that causes morbidity and mortality in humans. After infection with SARS-CoV, the acute lung injury caused by the...
10.
Venkataraman T, Frieman M
Antiviral Res
. 2017 Apr;
143:142-150.
PMID: 28390872
Many survivors of the 2003 outbreak of severe acute respiratory syndrome (SARS) developed residual pulmonary fibrosis with increased severity seen in older patients. Autopsies of patients that died from SARS...