Theo H van Dijk
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Explore the profile of Theo H van Dijk including associated specialties, affiliations and a list of published articles.
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76
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2940
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Recent Articles
1.
Palmiotti A, de Vries H, Hovingh M, Koehorst M, Mulder N, Verkade E, et al.
Biomedicines
. 2023 Sep;
11(9).
PMID: 37760936
Bile acids (BAs) and their signaling pathways have been identified as therapeutic targets for liver and metabolic diseases. We generated (KO) mice that were not able to convert chenodeoxycholic acid...
2.
Ling C, Versloot C, Arvidsson Kvissberg M, Hu G, Swain N, Horcas-Nieto J, et al.
EBioMedicine
. 2023 Sep;
96:104809.
PMID: 37738832
Background: The intestine of children with severe malnutrition (SM) shows structural and functional changes that are linked to increased infection and mortality. SM dysregulates the tryptophan-kynurenine pathway, which may impact...
3.
Rossi A, Oosterveer M, van Dijk T, Bleeker A, Koehorst M, Weinstein D, et al.
J Clin Endocrinol Metab
. 2023 Sep;
109(2):389-401.
PMID: 37690115
Context: Glycogen storage disease type Ia (GSDIa) is an inborn metabolic disorder characterized by impaired endogenous glucose production (EGP). Monitoring of patients with GSDIa is prioritized because of ongoing treatment...
4.
Vieira-Lara M, Reijne A, Koshian S, Ciapaite J, Abegaz F, Talarovicova A, et al.
Diabetes
. 2023 May;
72(7):872-883.
PMID: 37204269
Article Highlights: Exercise is a known strategy to improve insulin sensitivity (IS), whereas aging and a lipid-rich diet decrease IS. Using a tracer-based oral glucose tolerance test, we investigated how...
5.
Vieira-Lara M, Reijne A, Koshian S, Ciapaite J, Abegaz F, Talarovicova A, et al.
Diabetes
. 2023 Apr;
PMID: 37094362
Diet modulates the development of insulin resistance during aging. This includes tissue-specific alterations in insulin signaling and mitochondrial function, which ultimately affect glucose homeostasis. Exercise stimulates glucose clearance, mitochondrial lipid...
6.
Boers H, van Dijk T, Duchateau G, Mela D, Hiemstra H, Hoogenraad A, et al.
Eur J Clin Nutr
. 2023 Mar;
77(7):741-747.
PMID: 36944719
Background: Previous research has shown the efficacy of mulberry extracts for lowering post-prandial glucose (PPG) responses. The postulated mechanism is slowing of glucose absorption, but effects on glucose disposal or...
7.
Yang J, van Dijk T, Koehorst M, Havinga R, de Boer J, Kuipers F, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835544
Bile acids facilitate the intestinal absorption of dietary lipids and act as signalling molecules in the maintenance of metabolic homeostasis. Farnesoid X receptor (FXR) is a bile acid-responsive nuclear receptor...
8.
Paalvast Y, Zhou E, Rozendaal Y, Wang Y, Gerding A, van Dijk T, et al.
Nutrients
. 2022 Nov;
14(22).
PMID: 36432620
Within the human population, considerable variability exists between individuals in their susceptibility to develop obesity and dyslipidemia. In humans, this is thought to be caused by both genetic and environmental...
9.
Zhong S, Chevre R, Mayan D, Corliano M, Cochran B, Sem K, et al.
J Clin Invest
. 2022 Sep;
132(21).
PMID: 36107630
BACKGROUNDCytochrome P450 family 8 subfamily B member 1 (CYP8B1) generates 12α-hydroxylated bile acids (BAs) that are associated with insulin resistance in humans.METHODSTo determine whether reduced CYP8B1 activity improves insulin sensitivity,...
10.
Rossi A, Rutten M, van Dijk T, Bakker B, Reijngoud D, Oosterveer M, et al.
Front Endocrinol (Lausanne)
. 2022 Jul;
13:858832.
PMID: 35789807
Hypoglycemia results from an imbalance between glucose entering the blood compartment and glucose demand, caused by a defect in the mechanisms regulating postprandial glucose homeostasis. Hypoglycemia represents one of the...