Thangavel Alphonse Thanaraj
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Explore the profile of Thangavel Alphonse Thanaraj including associated specialties, affiliations and a list of published articles.
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97
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1510
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Recent Articles
1.
Thanaraj T, Abu-Farha M, Albatineh A, Channanath A, Melhem M, Chandy B, et al.
J Clin Endocrinol Metab
. 2025 Mar;
PMID: 40067965
Objective: Telomere plays a critical role in maintaining genomic stability, and its length serves as a marker of cellular aging. Emerging evidence projects telomere length as a clinical risk factor...
2.
Dashti M, Alkandari H, Malik M, Nizam R, John S, Jacob S, et al.
Front Cell Infect Microbiol
. 2025 Jan;
14():1444216.
PMID: 39844836
Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe complication arising from SARS-CoV-2 infection, with indications that rare inborn errors of immunity may play a role in its pathogenesis....
3.
Malik M, Dashti M, Jangid A, Channanath A, John S, Brojen Singh R, et al.
Brief Bioinform
. 2025 Jan;
26(1.
PMID: 39820247
In response to distinct cellular stresses, the p53 exhibits distinct dynamics. These p53 dynamics subsequently control cell fate. However, different stresses can generate the same p53 dynamics with different cell...
4.
Dashti M, Ali N, Alsaleh H, John S, Nizam R, Thanaraj T, et al.
Front Endocrinol (Lausanne)
. 2024 Dec;
15:1443737.
PMID: 39659613
Background: Numerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta cells and reducing oxidative phosphorylation in insulin-responsive...
5.
Nizam R, Malik M, Jacob S, Alsmadi O, Koistinen H, Tuomilehto J, et al.
Front Immunol
. 2024 Oct;
15:1376416.
PMID: 39464889
Introduction: Increasing evidence from human and animal model studies indicates the significant role of microRNAs (miRNAs) in pancreatic beta cell function, insulin signaling, immune responses, and pathogenesis of type 1...
6.
Dashti M, Malik M, Al-Matrouk A, Bhatti S, Nizam R, Jacob S, et al.
Front Pharmacol
. 2024 Oct;
15:1423636.
PMID: 39464636
Methods: We utilized the HLA-HD tool to extract, annotate, and analyse alleles from the exome data of 561 Kuwaiti individuals, sequenced on the Illumina HiSeq platform. HLA typing was conducted...
7.
Dashti M, Ali N, Alsaleh H, John S, Nizam R, Al-Mulla F, et al.
Front Endocrinol (Lausanne)
. 2024 Oct;
15:1449374.
PMID: 39464187
Background: The Kuwaiti and Qatari populations have a high prevalence of obesity, a major risk factor for various metabolic disorders. Previous studies have independently explored mitochondrial DNA (mtDNA) variations and...
8.
Baagar K, Alessa T, Abu-Farha M, Abubaker J, Alhumaidi H, Franco Ceruto J, et al.
Front Immunol
. 2024 Sep;
15:1369918.
PMID: 39308871
Background: Coronavirus disease 2019 (COVID-19) caused by the coronavirus SARS-CoV-2, has emerged as a rapidly spreading contagious disease across the globe. Recent studies showed that people with diabetes mellitus, severe...
9.
Jacob T, Sindhu S, Hasan A, Malik M, Arefanian H, Al-Rashed F, et al.
Front Microbiol
. 2024 Aug;
15:1407258.
PMID: 39165573
High-fat diets (HFDs) shape the gut microbiome and promote obesity, inflammation, and liver steatosis. Fish and soybean are part of a healthy diet; however, the impact of these fats, in...
10.
Alhaddad M, Mohammad A, Dashti K, John S, Bahbahani Y, Abu-Farha M, et al.
Heliyon
. 2024 Jul;
10(13):e33898.
PMID: 39071699
Background: Autosomal recessive polycystic kidney disease (ARPKD), a rare genetic disorder characterized by kidney cysts, shows complex clinical and genetic heterogeneity. This study aimed to explore the genetic landscape of...