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Fahd Al-Mulla

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Articles 325
Citations 7003
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Recent Articles
1.
Al-Rashed F, Alsaeed H, Akhter N, Alabduljader H, Al-Mulla F, Ahmad R
J Immunol . 2025 Mar; PMID: 40073081
The relationship between sleep deprivation, obesity, and systemic inflammation is a critical area of investigation due to its significant impact on health. While it is established that poor sleep adversely...
2.
Thanaraj T, Abu-Farha M, Albatineh A, Channanath A, Melhem M, Chandy B, et al.
J Clin Endocrinol Metab . 2025 Mar; PMID: 40067965
Objective: Telomere plays a critical role in maintaining genomic stability, and its length serves as a marker of cellular aging. Emerging evidence projects telomere length as a clinical risk factor...
3.
Alshawaf E, Marafie S, Abu-Farha M, Albatineh A, Alramah T, Albuhairi A, et al.
Biomedicines . 2025 Jan; 13(1. PMID: 39857685
Obesity and type 2 diabetes (T2D) are associated with significant alterations in various metabolic biomarkers. Isthmin-1 (Ism1) has recently emerged as a potential marker of metabolic health and was shown...
4.
Dashti M, Alkandari H, Malik M, Nizam R, John S, Jacob S, et al.
Front Cell Infect Microbiol . 2025 Jan; 14():1444216. PMID: 39844836
Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe complication arising from SARS-CoV-2 infection, with indications that rare inborn errors of immunity may play a role in its pathogenesis....
5.
Malik M, Dashti M, Jangid A, Channanath A, John S, Brojen Singh R, et al.
Brief Bioinform . 2025 Jan; 26(1. PMID: 39820247
In response to distinct cellular stresses, the p53 exhibits distinct dynamics. These p53 dynamics subsequently control cell fate. However, different stresses can generate the same p53 dynamics with different cell...
6.
Marafie S, Alshawaf E, Al-Mulla F, Abubaker J, Mohammad A
Pharmaceuticals (Basel) . 2025 Jan; 17(12. PMID: 39770519
: The mammalian target of the rapamycin (mTOR) signaling pathway is a central regulator of cell growth, proliferation, metabolism, and survival. Dysregulation of mTOR signaling contributes to many human diseases,...
7.
Dashti M, Ali N, Alsaleh H, John S, Nizam R, Thanaraj T, et al.
Front Endocrinol (Lausanne) . 2024 Dec; 15:1443737. PMID: 39659613
Background: Numerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta cells and reducing oxidative phosphorylation in insulin-responsive...
8.
Ghosh A, Chenier I, Leung Y, Oppong A, Peyot M, Murthy Madiraju S, et al.
iScience . 2024 Dec; 27(12):111292. PMID: 39640567
Angiopoietin-like protein 8 (Angptl8), expressed in the liver and adipocytes, forms a complex with Angptl3 or Angptl4, which regulates lipoprotein lipase and triglyceride metabolism. However, the precise functions of adipocyte...
9.
Alwadi Y, Al-Hemoud A, Khraishah H, Al-Mulla F, Koutrakis P, Ali H, et al.
J Epidemiol Glob Health . 2024 Dec; 14(4):1711-1719. PMID: 39621253
Background: The Middle East, especially Kuwait, is experiencing rapidly rising temperatures due to climate change. Cardiovascular diseases (CVD) are the leading cause of mortality in the country, and extreme heat...
10.
Arefanian H, Sindhu S, Al-Rashed F, Alzaid F, Madhoun A, Qaddoumi M, et al.
Front Endocrinol (Lausanne) . 2024 Nov; 15:1383448. PMID: 39544235
Introduction: Familial hypercholesterolemia, the highly prevalent form of dyslipidemia, is a well-known risk factor for premature heart disease and stroke worldwide. Statins, which inhibit 3-hydroxy 3-methylglutaryl coenzyme A (HMG-CoA) reductase,...