Sumi Elsa John
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Explore the profile of Sumi Elsa John including associated specialties, affiliations and a list of published articles.
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25
Citations
283
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Recent Articles
1.
Dashti M, Alkandari H, Malik M, Nizam R, John S, Jacob S, et al.
Front Cell Infect Microbiol
. 2025 Jan;
14():1444216.
PMID: 39844836
Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe complication arising from SARS-CoV-2 infection, with indications that rare inborn errors of immunity may play a role in its pathogenesis....
2.
Malik M, Dashti M, Jangid A, Channanath A, John S, Brojen Singh R, et al.
Brief Bioinform
. 2025 Jan;
26(1.
PMID: 39820247
In response to distinct cellular stresses, the p53 exhibits distinct dynamics. These p53 dynamics subsequently control cell fate. However, different stresses can generate the same p53 dynamics with different cell...
3.
Dashti M, Ali N, Alsaleh H, John S, Nizam R, Thanaraj T, et al.
Front Endocrinol (Lausanne)
. 2024 Dec;
15:1443737.
PMID: 39659613
Background: Numerous studies have linked mitochondrial dysfunction to the development of type 2 diabetes (T2D) by affecting glucose-stimulated insulin secretion in pancreatic beta cells and reducing oxidative phosphorylation in insulin-responsive...
4.
Dashti M, Ali N, Alsaleh H, John S, Nizam R, Al-Mulla F, et al.
Front Endocrinol (Lausanne)
. 2024 Oct;
15:1449374.
PMID: 39464187
Background: The Kuwaiti and Qatari populations have a high prevalence of obesity, a major risk factor for various metabolic disorders. Previous studies have independently explored mitochondrial DNA (mtDNA) variations and...
5.
Alhaddad M, Mohammad A, Dashti K, John S, Bahbahani Y, Abu-Farha M, et al.
Heliyon
. 2024 Jul;
10(13):e33898.
PMID: 39071699
Background: Autosomal recessive polycystic kidney disease (ARPKD), a rare genetic disorder characterized by kidney cysts, shows complex clinical and genetic heterogeneity. This study aimed to explore the genetic landscape of...
6.
Dashti M, Nizam R, John S, Melhem M, Channanath A, Alkandari H, et al.
Front Genet
. 2023 Nov;
14:1254833.
PMID: 37941991
gene, encoding hepatocyte nuclear factor 6, is involved in pancreas and liver development. mutations impair the function of pancreatic β-cells and control a transcriptional/epigenetic machinery regulating endocrine development. Homozygous nonsense...
7.
Hebbar P, Nizam R, John S, Antony D, Dashti M, Channanath A, et al.
Sci Rep
. 2023 Sep;
13(1):14978.
PMID: 37696853
Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous insulin. Higher estimates of heritability rates in monozygotic...
8.
Malik M, Dashti M, Fatima Y, Channanath A, John S, Brojen Singh R, et al.
Front Mol Neurosci
. 2023 Jul;
16:1217992.
PMID: 37475884
Introduction: Circadian rhythm maintains the sleep-wake cycle in biological systems. Various biological activities are regulated and modulated by the circadian rhythm, disruption of which can result in onset of diseases....
9.
Ali H, Naim M, Senum S, AlSahow A, Bahbahani Y, Abu-Farha M, et al.
Clin Kidney J
. 2023 Feb;
16(2):355-366.
PMID: 36755831
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal monogenic disease, characterized by bilateral accumulation of renal fluid-filled cysts leading to progressive renal volume enlargement and gradual...
10.
Dashti M, Nizam R, Hebbar P, Jacob S, John S, Channanath A, et al.
Sci Rep
. 2022 Jun;
12(1):11045.
PMID: 35773317
There has recently been a growing interest in examining the role of epigenetic modifications, such as DNA methylation, in the etiology of type 1 diabetes (T1D). This study aimed to...