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Thangavel Alphonse Thanaraj

Explore the profile of Thangavel Alphonse Thanaraj including associated specialties, affiliations and a list of published articles. Areas
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Articles 97
Citations 1510
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Recent Articles
11.
Ali H, Malik M, Abu-Farha M, Abubaker J, Cherian P, Al-Khairi I, et al.
J Endocr Soc . 2024 Jul; 8(8):bvae114. PMID: 38966710
Background: Diabetic nephropathy (DN) represents a major chronic kidney disorder and a leading cause of end-stage renal disease (ESRD). Small RNAs have been showing great promise as diagnostic markers as...
12.
Kochumon S, Malik M, Sindhu S, Arefanian H, Jacob T, Bahman F, et al.
Nutrients . 2024 Jun; 16(12). PMID: 38931284
Background: High-fat diets cause gut dysbiosis and promote triglyceride accumulation, obesity, gut permeability changes, inflammation, and insulin resistance. Both cocoa butter and fish oil are considered to be a part...
13.
Arefanian H, Madhoun A, Al-Rashed F, Alzaid F, Bahman F, Nizam R, et al.
Cells . 2024 Jun; 13(11. PMID: 38891081
This study unveils verapamil's compelling cytoprotective and proliferative effects on pancreatic β-cells amidst diabetic stressors, spotlighting its unforeseen role in augmenting cholecystokinin (CCK) expression. Through rigorous investigations employing MIN6 β-cells...
14.
Dashti M, Malik M, Nizam R, Jacob S, Al-Mulla F, Thanaraj T
Front Genet . 2024 Jun; 15:1407285. PMID: 38859936
HLA typing is a critical tool in both clinical and research applications at the individual and population levels. Benchmarking studies have indicated HLA-HD as the preferred tool for accurate and...
15.
Abdalla M, Abubaker J, Abu-Farha M, Al-Khairi I, Cherian P, Qaddoumi M, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38731797
Adipocyte P2 (aP2), also known as FABP4, is an adipokine that adipose tissue produces and expresses in macrophages. Its primary role is to facilitate the transportation of fatty acids across...
16.
Alramah T, Cherian P, Al-Khairi I, Abu-Farha M, Thanaraj T, Albatineh A, et al.
Front Endocrinol (Lausanne) . 2024 May; 15:1392675. PMID: 38711986
Obesity and Type 2 Diabetes Mellitus (T2DM) are intricate metabolic disorders with a multifactorial etiology, often leading to a spectrum of complications. Recent research has highlighted the impact of these...
17.
Ray A, Priya A, Malik M, Thanaraj T, Singh A, Mago P, et al.
Sci Rep . 2024 Mar; 14(1):7471. PMID: 38553458
Cardiovascular disease (CVD) is a collective term for disorders of the heart and blood vessels. The molecular events and biochemical pathways associated with CVD are difficult to study in clinical...
18.
Al-Rashed F, Arefanian H, Madhoun A, Bahman F, Sindhu S, Alsaeed H, et al.
Cells . 2024 Mar; 13(5). PMID: 38474427
Non-alcoholic fatty liver disease (NAFLD) is manifested by hepatic steatosis, insulin resistance, hepatocyte death, and systemic inflammation. Obesity induces steatosis and chronic inflammation in the liver. However, the precise mechanism...
19.
Materna M, Delmonte O, Bosticardo M, Momenilandi M, Conrey P, Charmeteau-De Muylder B, et al.
Science . 2024 Feb; 383(6686):eadh4059. PMID: 38422122
We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts at birth persisted over time, with normal memory...
20.
Ali H, Malik M, Abu-Farha M, Abubaker J, Cherian P, Nizam R, et al.
J Gene Med . 2024 Feb; 26(2):e3674. PMID: 38404150
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent monogenic renal disease progressing to end-stage renal disease. There is a pressing need for the identification of early ADPKD...