Takashi Nozawa
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Explore the profile of Takashi Nozawa including associated specialties, affiliations and a list of published articles.
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141
Citations
3102
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Recent Articles
1.
Ohta H, Nozawa T, Higuchi K, Meredith A, Morimoto Y, Satoh Y, et al.
Behav Brain Funct
. 2024 Dec;
20(1):36.
PMID: 39731174
The large-conductance calcium- and voltage-activated potassium (BK) channels, encoded by the KCNMA1 gene, play important roles in neuronal function. Mutations in KCNMA1 have been found in patients with various neurodevelopmental...
2.
Ohta H, Nozawa T, Nakano T, Morimoto Y, Ishizuka T
Neurobiol Aging
. 2024 Jul;
142:8-16.
PMID: 39029360
This study explores the impact of aging on reinforcement learning in mice, focusing on changes in learning rates and behavioral strategies. A 5-armed bandit task (5-ABT) and a computational Q-learning...
3.
Kawagishi Y, Kimeu T, Murase K, Yoshida A, Minowa-Nozawa A, Nozawa T, et al.
Microbiol Resour Announc
. 2024 Jun;
13(7):e0017924.
PMID: 38899901
is a member of the human skin microbiota as a commensal organism but could be an important opportunistic pathogen for immunocompromised individuals. Here, we report the complete genome sequence of...
4.
Iibushi J, Nozawa T, Toh H, Nakagawa I
iScience
. 2024 May;
27(5):109623.
PMID: 38706859
Invasive bacterial pathogens are internalized by host cells through endocytosis, which is regulated by a cascade of actin rearrangement signals triggered by host cell receptors or bacterial proteins delivered into...
5.
Arake M, Ohta H, Nozawa T, Satoh Y, Fujita M, Nakata T, et al.
Behav Brain Res
. 2024 Apr;
468:115015.
PMID: 38670533
This study examined the effect of knockout of KCNMA1 gene, coding for the BK channel, on cognitive and attentional functions in mice, with an aim to better understand its implications...
6.
Nozawa T, Toh H, Iibushi J, Kogai K, Minowa-Nozawa A, Satoh J, et al.
Nat Commun
. 2023 Oct;
14(1):6230.
PMID: 37802980
Xenophagy, a type of selective autophagy, is a bactericidal membrane trafficking that targets cytosolic bacterial pathogens, but the membrane homeostatic system to cope with bacterial infection in xenophagy is not...
7.
Yamazaki T, Nagatoishi S, Yamawaki T, Nozawa T, Matsunaga R, Nakakido M, et al.
J Biol Chem
. 2023 Sep;
299(10):105254.
PMID: 37716701
Listeriosis, caused by infection with Listeria monocytogenes, is a severe disease with a high mortality rate. The L. monocytogenes virulence factor, internalin family protein InlA, which binds to the host...
8.
Aikawa C, Shimizu A, Nakakido M, Murase K, Nozawa T, Tsumoto K, et al.
Biochem Biophys Res Commun
. 2023 Jul;
676:141-148.
PMID: 37516031
Cation diffusion facilitators (CDFs) are a large family of divalent metal transporters with broad specificities that contribute to intracellular metal homeostasis and toxicity in bacterial pathogens. Streptococcus pyogenes (Group A...
9.
Aoyama N, Kimura S, Matsui T, Nozawa T
Bioorg Med Chem Lett
. 2023 May;
90:129332.
PMID: 37196869
Herein, we developed a novel labelling precursor Fe-DFO-5 for plasmid DNA (pDNA) utilizing Zr as a radioisotope for PET imaging. Zr-labelled pDNA showed comparable gene expression to non-labelled pDNA. The...
10.
Yamada A, Hikichi M, Nozawa T, Nakagawa I
EMBO Rep
. 2021 Sep;
22(11):e52584.
PMID: 34515398
Xenophagy, also known as antibacterial selective autophagy, degrades invading bacterial pathogens such as group A Streptococcus (GAS) to defend cells. Although invading bacteria are known to be marked with ubiquitin...