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Takashi Nozawa

Explore the profile of Takashi Nozawa including associated specialties, affiliations and a list of published articles. Areas
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Articles 141
Citations 3102
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Recent Articles
11.
Murase K, Aikawa C, Nozawa T, Nakatake A, Sakamoto K, Kikuchi T, et al.
Front Cell Infect Microbiol . 2021 Aug; 11:711144. PMID: 34350134
Most bacteria naturally release spherical lipid-bilayered extracellular vesicles (EVs) containing proteins, nucleic acids, and virulence-related molecules, thus contributing to diverse biological functions including transport of virulence factors. The group A...
12.
Aikawa C, Kawashima K, Fukuzaki C, Nakakido M, Murase K, Nozawa T, et al.
Biochem Biophys Res Commun . 2021 Jun; 566:177-183. PMID: 34129965
Streptococcus pyogenes (Group A Streptococcus, GAS) causes a range of human diseases, including life-threatening and severe invasive GAS infections, such as streptococcal toxic shock syndrome (STSS). Several antibiotics, including penicillin,...
13.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy . 2021 Feb; 17(1):1-382. PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
14.
Nozawa T, Iibushi J, Toh H, Minowa-Nozawa A, Murase K, Aikawa C, et al.
mBio . 2021 Feb; 12(1). PMID: 33563838
Group A (GAS; ) is a major human pathogen that causes streptococcal pharyngitis, skin and soft tissue infections, and life-threatening conditions such as streptococcal toxic-shock syndrome. During infection, GAS not...
15.
Lin C, Nozawa T, Minowa-Nozawa A, Toh H, Hikichi M, Iibushi J, et al.
Front Cell Infect Microbiol . 2021 Jan; 10:583137. PMID: 33425778
Bacterial autophagy-a type of macroautophagy that is also termed xenophagy-selectively targets intracellular bacteria such as group A (GAS), a ubiquitous pathogen that causes numerous serious diseases, including pharyngitis, skin infections,...
16.
Minowa-Nozawa A, Nozawa T, Takamatsu D, Yoshida A, Murase K, Kikuchi T, et al.
Microbiol Resour Announc . 2020 Nov; 9(47). PMID: 33214308
is an important zoonotic pathogen that causes major economic problems in the pig industry worldwide and serious infections in humans, including meningitis and septicemia. Here, we report the complete genome...
17.
Murase K, Nozawa T, Aikawa C, Nagao M, Ikebe T, Yoshida A, et al.
Microbiol Resour Announc . 2020 Oct; 9(42). PMID: 33060279
(group A [GAS]) is a major human pathogen that occasionally causes severe and life-threatening invasive diseases. Here, we report the complete genome sequences of four GAS strains of three M...
18.
Nozawa T, Nakagawa I
Methods Mol Biol . 2020 May; 2136:223-231. PMID: 32430824
Group A Streptococcus (GAS) is one of the major human pathogens that can invade nonphagocytic cells. GAS internalized through endocytosis secretes the pore-forming toxin Streptolysin O (SLO) to escape into...
19.
Nozawa T, Sano S, Minowa-Nozawa A, Toh H, Nakajima S, Murase K, et al.
Nat Commun . 2020 Feb; 11(1):770. PMID: 32034138
Invading microbial pathogens can be eliminated selectively by xenophagy. Ubiquitin-mediated autophagy receptors are phosphorylated by TANK-binding kinase 1 (TBK1) and recruited to ubiquitinated bacteria to facilitate autophagosome formation during xenophagy,...
20.
Toh H, Lin C, Nakajima S, Aikawa C, Nozawa T, Nakagawa I
Front Cell Infect Microbiol . 2019 Dec; 9:398. PMID: 31850237
Group A (GAS) invades epithelial cells causing persistent infection. GAS has a variety of effector proteins that modulate host systems to affect their survival in host environments. The main effector...