Takashi Furusawa
Overview
Explore the profile of Takashi Furusawa including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
928
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Recent Articles
21.
Kurahashi T, Furusawa T, Ueda T, Bustin M
J Cell Biochem
. 2009 Nov;
109(1):49-57.
PMID: 19885867
Glucose homeostasis requires the coordinated actions of various organs and is critically dependent on the proper functioning of the various cell types present in the pancreatic Langerhans islets. Here we...
22.
Ueda T, Furusawa T, Kurahashi T, Tessarollo L, Bustin M
Mol Cell Biol
. 2009 Aug;
29(19):5264-76.
PMID: 19651901
Improper glucose-stimulated insulin secretion from pancreatic beta cells is a major factor in the onset of type 2 diabetes. We now report that HMGN3, a nuclear protein that binds to...
23.
Furusawa T, Bustin M
Methods Mol Biol
. 2009 Apr;
523:67-82.
PMID: 19381921
Visualization of the expression pattern of specific proteins during development and in adult tissues provides important clues as to their possible role in various cellular processes. Mouse is the organism...
24.
Furusawa T, Ko J, Birger Y, Bustin M
Gene Expr Patterns
. 2009 Mar;
9(5):289-95.
PMID: 19303948
Here we examine the expression pattern of HMGN1, a nucleosome binding protein that affects chromatin structure and activity, in the hair follicle and test whether loss of HMGN1 affects the...
25.
Shirakawa H, Rochman M, Furusawa T, Kuehn M, Horigome S, Haketa K, et al.
J Cell Biochem
. 2009 Jan;
106(4):651-8.
PMID: 19160411
We report that NSBP1, a nucleosome binding protein that affects the structure of chromatin, is highly expressed in mouse placenta. In Rcho-1 cells, which recapitulate the differentiation of trophoblast giant...
26.
Kim Y, Gerlitz G, Furusawa T, Catez F, Nussenzweig A, Oh K, et al.
Nat Cell Biol
. 2008 Dec;
11(1):92-6.
PMID: 19079244
Efficient and correct responses to double-stranded breaks (DSB) in chromosomal DNA are crucial for maintaining genomic stability and preventing chromosomal alterations that lead to cancer. The generation of DSB is...
27.
Belova G, Postnikov Y, Furusawa T, Birger Y, Bustin M
J Biol Chem
. 2008 Jan;
283(13):8080-8.
PMID: 18218636
The nucleosome-binding protein HMGN1 affects the structure and function of chromatin; however, its role in regulating specific gene expression in living cells is not fully understood. Here we use embryonic...
28.
Hock R, Furusawa T, Ueda T, Bustin M
Trends Cell Biol
. 2006 Dec;
17(2):72-9.
PMID: 17169561
The high mobility group (HMG) proteins are a superfamily of abundant and ubiquitous nuclear proteins that bind to DNA and nucleosomes and induce structural changes in the chromatin fiber. They...
29.
Birger Y, Davis J, Furusawa T, Rand E, Piatigorsky J, Bustin M
Differentiation
. 2006 Feb;
74(1):19-29.
PMID: 16466397
Corneal differentiation and maturation are associated with major changes in the expression levels of numerous genes, including those coding for the chromatin-binding high-mobility group (HMG) proteins. Here we report that...
30.
Furusawa T, Lim J, Catez F, Birger Y, Mackem S, Bustin M
Mol Cell Biol
. 2005 Dec;
26(2):592-604.
PMID: 16382150
We find that during embryogenesis the expression of HMGN1, a nuclear protein that binds to nucleosomes and reduces the compaction of the chromatin fiber, is progressively down-regulated throughout the entire...