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Takahiko Matsushita

Explore the profile of Takahiko Matsushita including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 290
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Recent Articles
1.
Miyairi K, Arai H, Matsushita T, Koyama T, Hatano K, Matsuoka K
Biomacromolecules . 2024 Aug; 25(8):5222-5232. PMID: 39089682
Fluorogenic glycomonomers have been used for biological evaluations, and water-soluble and Förster resonance energy transfer (FRET)-sensitive glycopolymers have also been reported. A FRET-sensitive polymer was conveniently prepared from a fluorogenic...
2.
Nakada J, Matsushita T, Koyama T, Hatano K, Matsuoka K
Bioorg Med Chem Lett . 2024 Jan; 99:129616. PMID: 38216097
Fischer's glycoside synthesis was applied to linker precursor alcohols of two different lengths having appropriate alkane chains to obtain the corresponding α-glycoside and it was found to be applicable with...
3.
Ishimaru Y, Moteki T, Suzuki M, Koyama T, Matsushita T, Hatano K, et al.
ACS Omega . 2023 Oct; 8(40):37451-37460. PMID: 37841131
A known tetraphenyl porphyrin (TPP) having an amino functional group [5-(4-aminophenyl)-10,15,20-(triphenyl)porphyrin] was converted into the corresponding monomer by means of condensation with acryloyl chloride. Simple radical polymerization of the porphyrin...
4.
Matsushita T, Nozaki M, Sunaga M, Koyama T, Hatano K, Matsuoka K
ACS Omega . 2023 Oct; 8(40):37329-37340. PMID: 37841120
Glycomonomers having -glycosidic linkages were prepared from a known glycosyl amine, -acetyl-d-glucosamine (GlcNAc). Radical polymerization of the glycomonomers gave a series of glycopolymers displaying various sugar densities, which were models...
5.
Matsushita T, Yamochi H, Omiya S, Koyama T, Hatano K, Matsuoka K
Bioorg Med Chem . 2023 Jul; 92:117422. PMID: 37523791
Polyacrylamides with various compositions of serine, aspartic acid, and histidine, which are the amino acids involved in the catalytic triad of natural serine protease chymotrypsin, were synthesized and their protein...
6.
Mohamad-Ramshan R, Ande C, Matsushita T, Haldimann K, Vasella A, Hobbie S, et al.
Tetrahedron . 2023 Apr; 135. PMID: 37035443
The design, synthesis and antiribosomal and antibacterial activity of two novel glycosides of the aminoglycoside antibiotic paromomycin are described. The first carries of 4-amino-4-deoxy-β-D-xylopyranosyl moiety at the paromomycin 4'-position and...
7.
Adachi R, Matsushita T, Koyama T, Hatano K, Matsuoka K
Polymers (Basel) . 2023 Feb; 15(4). PMID: 36850281
A polymerizable alcohol having 9 PEG repeats was prepared in order to mimic an oligosaccharide moiety. Sialyl α(2→3) lactose, which is known as a sugar moiety of GM3 ganglioside, was...
8.
Adachi R, Matsushita T, Koyama T, Hatano K, Matsuoka K
Bioorg Med Chem . 2023 Feb; 81:117209. PMID: 36787684
Glycopolymers having sialyl α2-3 lactose moieties via longer spacer arms were systematically prepared from the corresponding glycomonomers. Radical polymerization of glycomonomers gave a series of glycopolymers displaying various sugar densities....
9.
Matsushita T, Maruyama N, Koyama T, Hatano K, Matsuoka K
ACS Omega . 2022 Oct; 7(38):34554-34562. PMID: 36188280
To verify the potencies of dibromopyridazinediones with mono- and double-biotin groups, the functions as cysteine-selective biotinylation reagents were evaluated through conjugation with a goat anti-mouse IgG Fab fragment as a...
10.
Matsushita T, Toda N, Koyama T, Hatano K, Matsuoka K
Bioorg Chem . 2022 Aug; 128:106061. PMID: 35917748
We synthesized N-acetylglucosamine-terminated hexavalent carbosilane dendrimers and investigated their binding to wheat germ agglutinin (WGA). The glycodendrimers were prepared by the conjugation of 3-mercaptopropyl, 4-mercaptobutyl, or 5‑mercaptopentyl glycosides to maleimide-terminated...