Tadafumi Hashimoto
Overview
Explore the profile of Tadafumi Hashimoto including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
58
Citations
3029
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Murakami R, Watanabe H, Hashimoto H, Kashiwagi-Hakozaki M, Hashimoto T, Karch C, et al.
J Neurosci
. 2024 Apr;
44(24).
PMID: 38649269
Genetic variants in the () gene affect the onset and progression of Alzheimer's disease (AD). The Christchurch ( Ch) variant has been identified as the most prominent candidate for preventing...
2.
Watanabe H, Murakami R, Tsumagari K, Morimoto S, Hashimoto T, Imaizumi K, et al.
Stem Cell Reports
. 2023 Sep;
18(9):1854-1869.
PMID: 37657448
The APOE4 genotype is the strongest risk factor for the pathogenesis of sporadic Alzheimer's disease (AD), but the detailed molecular mechanism of APOE4-mediated synaptic impairment remains to be determined. In...
3.
Kishino Y, Matsukawa K, Matsumoto T, Miyazaki R, Wakabayashi T, Nonaka T, et al.
J Biol Chem
. 2022 Jun;
298(8):102191.
PMID: 35753345
Aberrant cytoplasmic accumulation of an RNA-binding protein, fused in sarcoma (FUS), characterizes the neuropathology of subtypes of ALS and frontotemporal lobar degeneration, although the effects of post-translational modifications of FUS,...
4.
Kaneshiro N, Komai M, Imaoka R, Ikeda A, Kamikubo Y, Saito T, et al.
iScience
. 2022 Mar;
25(3):103869.
PMID: 35243232
Endosomal anomalies because of vesicular traffic impairment have been indicated as an early pathology of Alzheimer'| disease (AD). However, the mechanisms and therapeutic targets remain unclear. We previously reported that...
5.
Ishida K, Yamada K, Nishiyama R, Hashimoto T, Nishida I, Abe Y, et al.
J Exp Med
. 2022 Feb;
219(3).
PMID: 35212707
Accumulation of tau has been implicated in various neurodegenerative diseases termed tauopathies. Tau is a microtubule-associated protein but is also actively released into the extracellular fluids including brain interstitial fluid...
6.
An H, Litscher G, Watanabe N, Wei W, Hashimoto T, Iwatsubo T, et al.
Neurobiol Dis
. 2021 Dec;
162:105585.
PMID: 34915152
Formation of cytoplasmic RNA-protein structures called stress granules (SGs) is a highly conserved cellular response to stress. Abnormal metabolism of SGs may contribute to the pathogenesis of (neuro)degenerative diseases such...
7.
Matsukawa K, Kukharsky M, Park S, Park S, Watanabe N, Iwatsubo T, et al.
RNA Biol
. 2021 Jan;
18(11):1546-1554.
PMID: 33427561
Pathological changes involving TDP-43 protein ('TDP-43 proteinopathy') are typical for several neurodegenerative diseases, including frontotemporal lobar degeneration (FTLD). FTLD-TDP cases are characterized by increased binding of TDP-43 to an abundant...
8.
Hashimoto T, Fujii D, Naka Y, Kashiwagi-Hakozaki M, Matsuo Y, Matsuura Y, et al.
Acta Neuropathol Commun
. 2020 Dec;
8(1):212.
PMID: 33287899
Massive deposition of amyloid β peptides (Aβ) as senile plaques (SP) characterizes the brain pathology of Alzheimer's disease (AD). SPs exhibit a variety of morphologies, although little is known about...
9.
Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Kawai K, et al.
Acta Neuropathol Commun
. 2020 May;
8(1):67.
PMID: 32398151
Aquaporin-4 (AQP4) has been suggested to be involved in the pathogenesis of neurodegenerative diseases including Alzheimer's disease (AD), which may be due to the modulation of neuroinflammation or the impairment...
10.
Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, et al.
Cell Rep
. 2019 Dec;
29(13):4362-4376.e6.
PMID: 31875546
Intramuscular motor innervation is an essential process in neuromuscular development. Recently, mutations in COL25A1, encoding CLAC-P/collagen XXV, have been linked to the development of a congenital cranial dysinnervation disorder (CCDD)....