Sylvain Bessonnard
Overview
Explore the profile of Sylvain Bessonnard including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
397
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Recent Articles
1.
Bessonnard S, Vandormael-Pournin S, Coqueran S, Cohen-Tannoudji M, Artus J
Stem Cells
. 2019 Mar;
37(7):888-898.
PMID: 30913328
Receptor tyrosine kinase signaling pathways are key regulators for the formation of the primitive endoderm (PrE) and the epiblast (Epi) from the inner cell mass (ICM) of the mouse preimplantation...
2.
Ginefra P, Filippi B, Donovan P, Bessonnard S, Constam D
Cell Rep
. 2018 Feb;
22(8):2176-2189.
PMID: 29466742
Furin trafficking, and that of related proprotein convertases (PCs), may regulate which substrates are accessible for endoproteolysis, but tools to directly test this hypothesis have been lacking. Here, we develop...
3.
Bessonnard S, Coqueran S, Vandormael-Pournin S, Dufour A, Artus J, Cohen-Tannoudji M
Sci Rep
. 2017 Sep;
7(1):12285.
PMID: 28947813
Inner cell Mass (ICM) specification into epiblast (Epi) and primitive endoderm (PrE) is an asynchronous and progressive process taking place between E3.0 to E3.75 under the control of the Fibroblast...
4.
Tosenberger A, Gonze D, Bessonnard S, Cohen-Tannoudji M, Chazaud C, Dupont G
NPJ Syst Biol Appl
. 2017 Jun;
3:16.
PMID: 28649443
Embryonic development is a self-organised process during which cells divide, interact, change fate according to a complex gene regulatory network and organise themselves in a three-dimensional space. Here, we model...
5.
Festuccia N, Dubois A, Vandormael-Pournin S, Gallego Tejeda E, Mouren A, Bessonnard S, et al.
Nat Cell Biol
. 2016 Oct;
18(11):1139-1148.
PMID: 27723719
Pluripotent mouse embryonic stem cells maintain their identity throughout virtually infinite cell divisions. This phenomenon, referred to as self-renewal, depends on a network of sequence-specific transcription factors (TFs) and requires...
6.
Minocha S, Bessonnard S, Sung T, Moret C, Constam D, Herr W
Dev Biol
. 2016 Aug;
418(1):75-88.
PMID: 27521049
Mammalian Host-Cell Factor 1 (HCF-1), a transcriptional co-regulator, plays important roles during the cell-division cycle in cell culture, embryogenesis as well as adult tissue. In mice, HCF-1 is encoded by...
7.
Bessonnard S, Gonze D, Dupont G
Med Sci (Paris)
. 2016 Mar;
32(2):192-7.
PMID: 26936177
Upon its implantation in the uterus of the mother in mammals, the embryo is composed by three morphologically distinct tissues: the Epiblast (Epi), the Trophectoderm (TE) and the Primitive Endoderm...
8.
de Mot L, Gonze D, Bessonnard S, Chazaud C, Goldbeter A, Dupont G
Biophys J
. 2016 Feb;
110(3):710-722.
PMID: 26840735
During development, interactions between transcription factors control the specification of different cell fates. The regulatory networks of genetic interactions often exhibit multiple stable steady states; such multistability provides a common...
9.
Bessonnard S, Mesnard D, Constam D
J Cell Biol
. 2015 Sep;
210(7):1185-97.
PMID: 26416966
The first cell differentiation in mammalian embryos segregates polarized trophectoderm cells from an apolar inner cell mass (ICM). This lineage decision is specified in compacted morulae by cell polarization and...
10.
Bessonnard S, de Mot L, Gonze D, Barriol M, Dennis C, Goldbeter A, et al.
Development
. 2014 Sep;
141(19):3637-48.
PMID: 25209243
During blastocyst formation, inner cell mass (ICM) cells differentiate into either epiblast (Epi) or primitive endoderm (PrE) cells, labeled by Nanog and Gata6, respectively, and organized in a salt-and-pepper pattern....