Michel Cohen-Tannoudji
Overview
Explore the profile of Michel Cohen-Tannoudji including associated specialties, affiliations and a list of published articles.
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50
Citations
1072
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Recent Articles
1.
Geiselmann A, Micouin A, Vandormael-Pournin S, Laville V, Chervova A, Mella S, et al.
Dev Cell
. 2024 Oct;
60(2):204-219.e6.
PMID: 39461340
The inner cell mass (ICM) of early mouse embryos is specified into epiblast (Epi) and primitive endoderm (PrE) lineages during blastocyst formation. The antagonistic transcription factors (TFs) NANOG and GATA-binding...
2.
Festuccia N, Vandormael-Pournin S, Chervova A, Geiselmann A, Langa-Vives F, Coux R, et al.
Science
. 2024 Oct;
386(6717):eadg7325.
PMID: 39361745
Early embryogenesis is driven by transcription factors (TFs) that first activate the zygotic genome and then specify the lineages constituting the blastocyst. Although the TFs specifying the blastocyst's lineages are...
3.
Dubois A, Vincenti L, Chervova A, Greenberg M, Vandormael-Pournin S, Bourchis D, et al.
Development
. 2022 Aug;
149(17).
PMID: 35976266
Mouse embryonic stem cells have an inherent propensity to explore gene regulatory states associated with either self-renewal or differentiation. This property depends on ERK, which downregulates pluripotency genes such as...
4.
Bernard L, Dubois A, Heurtier V, Fischer V, Gonzalez I, Chervova A, et al.
Nucleic Acids Res
. 2022 Jun;
50(13):7367-7379.
PMID: 35762231
Histone H3 Lysine 9 (H3K9) methylation, a characteristic mark of heterochromatin, is progressively implemented during development to contribute to cell fate restriction as differentiation proceeds. Accordingly, in undifferentiated and pluripotent...
5.
Allegre N, Chauveau S, Dennis C, Renaud Y, Meistermann D, Estrella L, et al.
Nat Commun
. 2022 Jun;
13(1):3550.
PMID: 35729116
The epiblast is the source of all mammalian embryonic tissues and of pluripotent embryonic stem cells. It differentiates alongside the primitive endoderm in a "salt and pepper" pattern from inner...
6.
Ngondo R, Cohen-Tannoudji M, Ciaudo C
STAR Protoc
. 2020 Dec;
1(3):100127.
PMID: 33377021
Mouse embryonic stem cells (mESCs) are a powerful model to study early mouse development. These blastocyst-derived cells can maintain pluripotency and differentiate into the three embryonic germ layers and an...
7.
Vandormael-Pournin S, Frachon E, Gobaa S, Cohen-Tannoudji M
Methods Mol Biol
. 2020 Sep;
2214:11-30.
PMID: 32944900
The mouse preimplantation embryo is an excellent system for studying how mammalian cells organize dynamically into increasingly complex structures. Accessible to experimental and genetic manipulations, its normal or perturbed development...
8.
Kumamoto T, Maurinot F, Barry-Martinet R, Vaslin C, Vandormael-Pournin S, Le M, et al.
Neuron
. 2020 Jun;
107(4):617-630.e6.
PMID: 32559415
Stable genomic integration of exogenous transgenes is essential in neurodevelopmental and stem cell studies. Despite tools driving increasingly efficient genomic insertion with DNA vectors, transgenesis remains fundamentally hindered by the...
9.
Raveux A, Stedman A, Coqueran S, Vandormael-Pournin S, Owens N, Romagnolo B, et al.
Cell Death Differ
. 2020 May;
27(10):2872-2887.
PMID: 32355182
Ribosome biogenesis inhibition causes cell cycle arrest and apoptosis through the activation of tumor suppressor-dependent surveillance pathways. These responses are exacerbated in cancer cells, suggesting that targeting ribosome synthesis may...
10.
Owens N, Papadopoulou T, Festuccia N, Tachtsidi A, Gonzalez I, Dubois A, et al.
Elife
. 2019 Oct;
8.
PMID: 31599722
The access of Transcription Factors (TFs) to their cognate DNA binding motifs requires a precise control over nucleosome positioning. This is especially important following DNA replication and during mitosis, both...