Steven T Sizemore
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Explore the profile of Steven T Sizemore including associated specialties, affiliations and a list of published articles.
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27
Citations
473
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Recent Articles
1.
Gupta A, Choueiry F, Reardon J, Pramod N, Kulkarni A, Shankar E, et al.
bioRxiv
. 2025 Jan;
PMID: 39868332
Invasive Lobular Carcinoma (ILC), a distinct subtype of breast cancer is hallmarked by E-Cadherin loss, slow proliferation, and strong hormone receptor positivity. ILC faces significant challenges in clinical management due...
2.
Han D, Spehar J, Richardson D, Leelananda S, Chakravarthy P, Grecco S, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272901
Breast cancer (BC) is the most frequent cancer and second-leading cause of cancer deaths in women in the United States. While RAS mutations are infrequent in BC, triple-negative (TN) and...
3.
Singh D, Qiu Z, Jonathan S, Fa P, Thomas H, Prasad C, et al.
Cancer Lett
. 2024 Jul;
598:217110.
PMID: 38986733
PP2A B55α, encoded by PPP2R2A, acts as a regulatory subunit of the serine/threonine phosphatase PP2A. Despite a frequent loss of heterozygosity of PPP2R2A in cases of non-small cell lung cancer...
4.
Anstine L, Majmudar P, Aponte A, Singh S, Zhao R, Weber-Bonk K, et al.
Cancer Res
. 2023 Jan;
83(7):997-1015.
PMID: 36696357
Significance: Transcriptional corepressor TLE3 actively suppresses SOX9 and TGFβ transcriptional programs to sustain the luminal lineage identity of breast cancer cells and to inhibit metastatic progression.
5.
Jones C, Sharick J, Sizemore S, Cukierman E, Strohecker A, Leight J
Cancer Res Commun
. 2022 Dec;
2(11):1471-1486.
PMID: 36530465
Extracellular matrix alignment contributes to metastasis in a number of cancers and is a known prognostic stromal factor; however, the mechanisms controlling matrix organization remain unclear. Cancer-associated fibroblasts (CAF) play...
6.
Richardson D, Spehar J, Han D, Chakravarthy P, Sizemore S
Cells
. 2022 May;
11(10).
PMID: 35626682
RALA and RALB are highly homologous small G proteins belonging to the RAS superfamily. Like other small GTPases, the RALs are molecular switches that can be toggled between inactive GDP-bound...
7.
Thies K, Cole M, Schafer R, Spehar J, Richardson D, Steck S, et al.
Breast Cancer Res
. 2021 Jun;
23(1):65.
PMID: 34118960
Background: Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of...
8.
Zhang Y, Asad S, Weber Z, Tallman D, Nock W, Wyse M, et al.
BMC Cancer
. 2021 May;
21(1):568.
PMID: 34006255
Background: Triple-negative breast cancer (TNBC) is a heterogeneous disease and we have previously shown that rapid relapse of TNBC is associated with distinct sociodemographic features. We hypothesized that rapid versus...
9.
Jones C, Sharick J, Colbert S, Shukla V, Zent J, Ostrowski M, et al.
PLoS One
. 2021 Feb;
16(2):e0245653.
PMID: 33534863
Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated...
10.
Seachrist D, Hannigan M, Ingles N, Webb B, Weber-Bonk K, Yu P, et al.
J Biol Chem
. 2020 Jun;
295(33):11707-11719.
PMID: 32576660
The phenotypes of each breast cancer subtype are defined by their transcriptomes. However, the transcription factors that regulate differential patterns of gene expression that contribute to specific disease outcomes are...