Jonathan M Spehar
Overview
Explore the profile of Jonathan M Spehar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
45
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Han D, Spehar J, Richardson D, Leelananda S, Chakravarthy P, Grecco S, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272901
Breast cancer (BC) is the most frequent cancer and second-leading cause of cancer deaths in women in the United States. While RAS mutations are infrequent in BC, triple-negative (TN) and...
2.
Richardson D, Spehar J, Han D, Chakravarthy P, Sizemore S
Cells
. 2022 May;
11(10).
PMID: 35626682
RALA and RALB are highly homologous small G proteins belonging to the RAS superfamily. Like other small GTPases, the RALs are molecular switches that can be toggled between inactive GDP-bound...
3.
Thies K, Cole M, Schafer R, Spehar J, Richardson D, Steck S, et al.
Breast Cancer Res
. 2021 Jun;
23(1):65.
PMID: 34118960
Background: Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of...
4.
Geisler J, Spehar J, Steck S, Bratasz A, Shakya R, Powell K, et al.
J Vis Exp
. 2020 Jun;
(160).
PMID: 32568247
Metastatic spread of cancer is an unfortunate consequence of disease progression, aggressive cancer subtypes, and/or late diagnosis. Brain metastases are particularly devastating, difficult to treat, and confer a poor prognosis....
5.
Thies K, Hammer A, Hildreth 3rd B, Steck S, Spehar J, Kladney R, et al.
Cancer Res
. 2020 Apr;
81(3):606-618.
PMID: 32327406
Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand...
6.
Quinones R, Iuliucci R, Behnke G, Brown R, Shoup D, Riedel T, et al.
J Pharm Biomed Anal
. 2017 Oct;
148:163-169.
PMID: 29035811
Solid-state nuclear magnetic resonance (SS-NMR) spectroscopy has become a common technique to study polymorphism in pharmaceutical solids at high-resolution. However, high-throughput application of high resolution SS-NMR spectroscopy is severely limited...