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Steven A Vokes

Explore the profile of Steven A Vokes including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1273
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Recent Articles
1.
Ramachandran J, Chen W, Lex R, Windsor K, Lee H, Wang T, et al.
Dev Biol . 2023 Oct; 504:128-136. PMID: 37805104
Transcriptional responses to the Hedgehog (HH) signaling pathway are primarily modulated by GLI repression in the mouse limb. Previous studies suggested a role for the BAF chromatin remodeling complex in...
2.
Ramachandran J, Chen W, Lex R, Windsor K, Lee H, Wang T, et al.
bioRxiv . 2023 Feb; PMID: 36798239
Transcriptional responses to the Hedgehog (HH) signaling pathway are primarily modulated by GLI repression in the mouse limb. Previous studies suggested a role for the BAF chromatin remodeling complex in...
3.
Ramachandran J, Zhou W, Bardenhagen A, Nasr T, Yates E, Zorn A, et al.
Elife . 2022 Nov; 11. PMID: 36398878
The larynx enables speech while regulating swallowing and respiration. Larynx function hinges on the laryngeal epithelium which originates as part of the anterior foregut and undergoes extensive remodeling to separate...
4.
Lex R, Vokes S
Bioessays . 2022 Oct; 44(12):e2200139. PMID: 36251875
Hedgehog (HH) signaling is a conserved pathway that drives developmental growth and is essential for the formation of most organs. The expression of HH target genes is regulated by a...
5.
Lee H, Vokes S
Dev Cell . 2022 Sep; 57(17):2041-2042. PMID: 36099905
Hedgehog signaling has traditionally been considered to be a morphogen for digits. In this issue of Developmental Cell, Zhu et al. show that a brief exposure to Sonic Hedgehog is...
6.
Lex R, Zhou W, Ji Z, Falkenstein K, Schuler K, Windsor K, et al.
Nat Commun . 2022 Feb; 13(1):808. PMID: 35145123
The Hedgehog (HH) pathway regulates a spectrum of developmental processes through the transcriptional mediation of GLI proteins. GLI repressors control tissue patterning by preventing sub-threshold activation of HH target genes,...
7.
Lex R, Ji Z, Falkenstein K, Zhou W, Henry J, Ji H, et al.
Elife . 2020 Jan; 9. PMID: 31989924
Transcriptional repression needs to be rapidly reversible during embryonic development. This extends to the Hedgehog pathway, which primarily serves to counter GLI repression by processing GLI proteins into transcriptional activators....
8.
Liu Z, Ramachandran J, Vokes S, Gray R
Dis Model Mech . 2019 Dec; 12(12). PMID: 31848143
Idiopathic scoliosis (IS) is the most common type of musculoskeletal defect affecting children worldwide, and is classified by age of onset, location and degree of spine curvature. Although rare, IS...
9.
Ramachandran J, Liu Z, Gray R, Vokes S
Dev Biol . 2019 Aug; 456(2):154-163. PMID: 31442442
During skeletal development, limb progenitors become specified as chondrocytes and subsequently differentiate into specialized cartilage compartments. We previously showed that the arginine dimethyl transferase, PRMT5, is essential for regulating the...
10.
Hoffmann A, Yang X, Burnicka-Turek O, Bosman J, Ren X, Xie L, et al.
PLoS Genet . 2016 Dec; 12(12):e1006533. PMID: 28033319
[This corrects the article DOI: 10.1371/journal.pgen.1004604.].