Stephen J Renaud
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Explore the profile of Stephen J Renaud including associated specialties, affiliations and a list of published articles.
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37
Citations
817
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Recent Articles
1.
Biggar E, Thomas R, Lave M, Jaju Bhattad G, Rajakumar N, Renaud S
Placenta
. 2025 Mar;
163:51-60.
PMID: 40081234
Introduction: Maternal immune activation (MIA), characterized by increased circulating inflammatory mediators during pregnancy, is associated with adverse pregnancy outcomes and neurodevelopmental deficits in offspring. These health outcomes often manifest differently...
2.
Chowdhury D, Jang C, Lajoie P, Renaud S
Front Endocrinol (Lausanne)
. 2025 Jan;
15:1525189.
PMID: 39758342
The placenta is a temporary organ that forms during pregnancy and is essential for fetal development and maternal health. As an endocrine organ, proper placental function requires continual production, folding,...
3.
Jeyarajah M, Patterson V, Jaju Bhattad G, Zhao L, Whitehead S, Renaud S
Commun Biol
. 2024 Oct;
7(1):1254.
PMID: 39363116
Congenital heart defects are leading causes of neonatal mortality and are often associated with placental abnormalities, but mechanisms linking placenta and heart development are poorly understood. Herein, we investigated a...
4.
Cinkornpumin J, Kwon S, Prandstetter A, Maxian T, Sirois J, Goldberg J, et al.
bioRxiv
. 2024 Sep;
PMID: 39314437
The placenta develops alongside the embryo and nurtures fetal development to term. During the first stages of embryonic development, due to low blood circulation, the blood and ambient oxygen supply...
5.
Renaud S
Genes Dev
. 2024 Aug;
38(15-16):695-697.
PMID: 39174324
In the human placenta, cell fusion is crucial for forming the syncytiotrophoblast, a multinucleated giant cell essential for maintaining pregnancy and ensuring fetal health. The formation of the syncytiotrophoblast is...
6.
Jaremek A, Renaud S
Methods Mol Biol
. 2023 Nov;
2728:87-98.
PMID: 38019393
The fusion of cytotrophoblasts into a multinucleated syncytiotrophoblast is essential for placental development. For studies investigating syncytiotrophoblast formation, various methods are available to analyze the fusion efficiency of trophoblast cells...
7.
Baines K, Klausner M, Patterson V, Renaud S
Front Cell Dev Biol
. 2023 May;
11:1079164.
PMID: 37152295
Uterine Natural Killer (NK) cells are the predominant immune cells within the decidua during early pregnancy. These cells are thought to regulate aspects of decidualization and placental development, but their...
8.
Jaremek A, Shaha S, Jeyarajah M, Jaju Bhattad G, Chowdhury D, Riddell M, et al.
Am J Pathol
. 2023 Apr;
193(7):846-865.
PMID: 37028593
Preeclampsia (PE) is a common and serious complication of pregnancy with no cure except premature delivery. The root cause of PE is improper development of the placenta-the temporary organ supporting...
9.
Jeyarajah M, Jaju Bhattad G, Kelly R, Baines K, Jaremek A, Yang F, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(49):e2203071119.
PMID: 36442132
Remodeling of the uterine vasculature by invasive extravillous trophoblasts (EVTs) is a critical aspect of human placentation. Insufficient EVT invasion can lead to severe obstetrical complications like preeclampsia, intrauterine growth...
10.
Hilton L, Ratsep M, VandenBroek M, Jafri S, Laverty K, Mitchell M, et al.
Hypertension
. 2022 Aug;
79(11):2493-2504.
PMID: 36043416
Background: Natural killer (NK) cell impairment is a feature of pulmonary arterial hypertension (PAH) and contributes to vascular remodeling in animal models of disease. Although mutations in , the gene...