Stephen J Renaud
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Explore the profile of Stephen J Renaud including associated specialties, affiliations and a list of published articles.
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37
Citations
817
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Recent Articles
11.
Renaud S, Jeyarajah M
Cell Mol Life Sci
. 2022 Jul;
79(8):433.
PMID: 35859055
In humans, cell fusion is restricted to only a few cell types under normal conditions. In the placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant multinucleated...
12.
Haddad F, Patel S, Doornaert E, De Oliveira C, Allman B, Baines K, et al.
Brain Behav Immun Health
. 2022 Jun;
23:100473.
PMID: 35668725
Maternal infections during pregnancy are linked with an increased risk for disorders like Autism Spectrum Disorder and schizophrenia in the offspring. Although precise mechanisms are still unclear, clinical and preclinical...
13.
Roberts H, Woodman A, Baines K, Jeyarajah M, Bourque S, Renaud S
Endocrinology
. 2021 Oct;
162(12).
PMID: 34647996
Iron deficiency, which occurs when iron demands chronically exceed intake, is prevalent in pregnant women. Iron deficiency during pregnancy poses major risks for the baby, including fetal growth restriction and...
14.
Jaremek A, Jeyarajah M, Jaju Bhattad G, Renaud S
Front Cell Dev Biol
. 2021 Jul;
9:674162.
PMID: 34211975
Proper development of the placenta is vital for pregnancy success. The placenta regulates exchange of nutrients and gases between maternal and fetal blood and produces hormones essential to maintain pregnancy....
15.
Gragasin F, Ospina M, Serrano-Lomelin J, Kim S, Kokotilo M, Woodman A, et al.
J Clin Med
. 2021 Apr;
10(5).
PMID: 33801215
Background: Both high and low placental weights are associated with adverse pregnancy outcomes. Maternal hemoglobin levels can influence placental weight, but the evidence is conflicting. Since maternal hemoglobin does not...
16.
Roberts H, Bourque S, Renaud S
Reproduction
. 2021 Jan;
160(4):R65-R78.
PMID: 33434171
Iron is an essential mineral that participates in oxygen transport, DNA synthesis and repair, and as a cofactor for various cellular processes. Iron deficiency is the most common nutritional deficiency...
17.
Rampersaud A, Dunk C, Lye S, Renaud S
Mol Hum Reprod
. 2020 Sep;
26(11):850-865.
PMID: 32898274
A critical component of early human placental development includes migration of extravillous trophoblasts (EVTs) into the decidua. EVTs migrate toward and displace vascular smooth muscle cells (SMCs) surrounding several uterine...
18.
Baines K, Hillier D, Haddad F, Rajakumar N, Schmid S, Renaud S
Front Immunol
. 2020 Jun;
11:1145.
PMID: 32582210
Maternal immune activation (MIA) caused by exposure to pathogens or inflammation during critical periods of neurodevelopment is a major risk factor for behavioral deficits and psychiatric illness in offspring. A...
19.
Jaju Bhattad G, Jeyarajah M, McGill M, Dumeaux V, Okae H, Arima T, et al.
Cell Death Dis
. 2020 May;
11(5):311.
PMID: 32366868
Cell fusion occurs when several cells combine to form a multinuclear aggregate (syncytium). In human placenta, a syncytialized trophoblast (syncytiotrophoblast) layer forms the primary interface between maternal and fetal tissue,...
20.
Jeyarajah M, Jaju Bhattad G, Hillier D, Renaud S
Cells
. 2020 Apr;
9(4).
PMID: 32244352
Trophoblasts are the first cell type to be specified during embryogenesis, and they are essential for placental morphogenesis and function. Trophoblast stem (TS) cells are the progenitor cells for all...