Stephane J C Mancini
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Explore the profile of Stephane J C Mancini including associated specialties, affiliations and a list of published articles.
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33
Citations
799
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Recent Articles
21.
Mancini S, Elantak L, Boned A, Espeli M, Guerlesquin F, Schiff C
Methods Mol Biol
. 2014 Sep;
1207:169-84.
PMID: 25253140
Galectin-1 (GAL1) is a pre-B cell receptor (pre-BCR) ligand that induces pre-BCR clustering and leads to efficient pre-B cell proliferation and differentiation in the bone marrow. To study pre-BCR-GAL1 interactions...
22.
Anginot A, Espeli M, Chasson L, Mancini S, Schiff C
J Immunol
. 2013 Apr;
190(11):5526-33.
PMID: 23616571
Galectin-1 (GAL1) is an S-type lectin with multiple functions, including the control of B cell homeostasis. GAL1 expression was reported to be under the control of the plasma cell master...
23.
Arcangeli M, Frontera V, Bardin F, Obrados E, Adams S, Chabannon C, et al.
Blood
. 2011 Aug;
118(17):4609-19.
PMID: 21868569
In adult mammals, hematopoietic stem cells (HSCs) reside in the bone marrow (BM) and are maintained in a quiescent and undifferentiated state through adhesive interactions with specialized microenvironmental niches. Although...
24.
Meng W, Yunk L, Wang L, Maganty A, Xue E, Cohen P, et al.
J Immunol
. 2011 Jul;
187(4):1835-44.
PMID: 21746964
B cells are subjected to selection at multiple checkpoints during their development. The selection of Ab H chains is difficult to study because of the large diversity of the CDR3....
25.
Mourcin F, Breton C, Tellier J, Narang P, Chasson L, Jorquera A, et al.
Blood
. 2011 Apr;
117(24):6552-61.
PMID: 21511956
In the bone marrow (BM), stromal cells constitute a supportive tissue indispensable for the generation of pro-B/pre-BI, pre-BII, and immature B lymphocytes. IL-7-producing stromal cells constitute a cellular niche for...
26.
Mansour A, Anginot A, Mancini S, Schiff C, Carle G, Wakkach A, et al.
Cell Res
. 2011 Feb;
21(7):1102-15.
PMID: 21321604
B-cell development is dependent on the interactions between B-cell precursors and bone marrow stromal cells, but the role of osteoclasts (OCLs) in this process remains unknown. B lymphocytopenia is a...
27.
Espeli M, Mancini S, Breton C, Poirier F, Schiff C
Blood
. 2009 Mar;
113(23):5878-86.
PMID: 19329777
Activation of the pre-B-cell receptor (pre-BCR) in the bone marrow depends on both tonic and ligand-induced signaling and leads to pre-BII-cell proliferation and differentiation. Using normal mouse bone marrow pre-BII...
28.
Ferrero I, Mancini S, Grosjean F, Wilson A, Otten L, MacDonald H
J Immunol
. 2006 Oct;
177(9):6038-43.
PMID: 17056529
During thymus development, immature T cells become committed to two distinct lineages based upon expression of alphabeta or gammadelta TCR. In the alphabeta lineage, developing thymocytes progressively extinguish transcription of...
29.
Espeli M, Rossi B, Mancini S, Roche P, Gauthier L, Schiff C
Semin Immunol
. 2005 Dec;
18(1):56-66.
PMID: 16337808
B cell development in the bone marrow is a highly regulated process and expression of a functional pre-BCR represents a crucial checkpoint, common to human and mouse. In this review,...
30.
Mancini S, Mantei N, Dumortier A, Suter U, MacDonald H, Radtke F
Blood
. 2004 Nov;
105(6):2340-2.
PMID: 15550486
Jagged1-mediated Notch signaling has been suggested to be critically involved in hematopoietic stem cell (HSC) self-renewal. Unexpectedly, we report here that inducible Cre-loxP-mediated inactivation of the Jagged1 gene in bone...