Stefania Di Marco
Overview
Explore the profile of Stefania Di Marco including associated specialties, affiliations and a list of published articles.
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27
Citations
1451
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Recent Articles
1.
Hannoun Z, Wee E, Crook A, Colloca S, Di Marco S, Hanke T
Vaccines (Basel)
. 2022 Jun;
10(6).
PMID: 35746566
In this study, we invented and construct novel candidate HIV-1 vaccines. Through genetic and protein engineering, we unknowingly constructed an HIV-1-derived transgene with a homopolymeric run of 11 cytidines, which...
2.
Payne R, Silk S, Elias S, Miura K, Diouf A, Galaway F, et al.
JCI Insight
. 2017 Nov;
2(21).
PMID: 29093263
The development of a highly effective vaccine remains a key strategic goal to aid the control and eventual eradication of Plasmodium falciparum malaria. In recent years, the reticulocyte-binding protein homolog...
3.
Osman M, Mistry A, Keding A, Gabe R, Cook E, Forrester S, et al.
PLoS Negl Trop Dis
. 2017 May;
11(5):e0005527.
PMID: 28498840
Background: Visceral leishmaniasis (VL or kala azar) is the most serious form of human leishmaniasis, responsible for over 20,000 deaths annually, and post kala azar dermal leishmaniasis (PKDL) is a...
4.
Kelly C, Swadling L, Capone S, Brown A, Richardson R, Halliday J, et al.
Hepatology
. 2015 Oct;
63(5):1455-70.
PMID: 26474390
Unlabelled: Adenoviral vectors encoding hepatitis C virus (HCV) nonstructural (NS) proteins induce multispecific, high-magnitude, durable CD4(+) and CD8(+) T-cell responses in healthy volunteers. We assessed the capacity of these vaccines...
5.
Green C, Scarselli E, Sande C, Thompson A, de Lara C, Taylor K, et al.
Sci Transl Med
. 2015 Aug;
7(300):300ra126.
PMID: 26268313
Respiratory syncytial virus (RSV) causes respiratory infection in annual epidemics, with infants and the elderly at particular risk of developing severe disease and death. However, despite its importance, no vaccine...
6.
Ewer K, Rampling T, Venkatraman N, Bowyer G, Wright D, Lambe T, et al.
N Engl J Med
. 2015 Jan;
374(17):1635-46.
PMID: 25629663
Background: The West African outbreak of Ebola virus disease that peaked in 2014 has caused more than 11,000 deaths. The development of an effective Ebola vaccine is a priority for...
7.
dAlessandro L, Petrini M, Ferrante M, Di Marco S, Trubiani O, Spoto G
Oral Surg Oral Med Oral Pathol Oral Radiol
. 2012 Aug;
116(5):e317-23.
PMID: 22921442
Objective: The aim of this work was to evaluate both the level of endogenous cyclic nucleotides cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cAMP) and phosphodiesterase activity in mesenchymal...
8.
Narjes F, Crescenzi B, Ferrara M, Habermann J, Colarusso S, Ferreira M, et al.
J Med Chem
. 2010 Dec;
54(1):289-301.
PMID: 21141896
Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication...
9.
Ni Y, Di Marco S, Condra J, Peterson L, Wang W, Wang F, et al.
J Lipid Res
. 2010 Oct;
52(1):78-86.
PMID: 20959675
Proprotein convertase subtilisin-like/kexin type 9 (PCSK9) regulates LDL cholesterol levels by inhibiting LDL receptor (LDLr)-mediated cellular LDL uptake. We have identified a fragment antigen-binding (Fab) 1D05 which binds PCSK9 with...
10.
Ni Y, Condra J, Orsatti L, Shen X, Di Marco S, Pandit S, et al.
J Biol Chem
. 2010 Feb;
285(17):12882-91.
PMID: 20172854
PCSK9 binds to the low density lipoprotein receptor (LDLR) and leads to LDLR degradation and inhibition of plasma LDL cholesterol clearance. Consequently, the role of PCSK9 in modulating circulating LDL...