Michael Rowley
Overview
Explore the profile of Michael Rowley including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
69
Citations
1116
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0
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Recent Articles
1.
Rowley M, Kurihara T, Ortiz-Weissberg D, Kulig K
Acta Bioeng Biomech
. 2024 Feb;
25(1):91-99.
PMID: 38314582
Purpose: Morphological differences between the two primary great toe flexors - flexor hallucis longus (FHL) and flexor hallucis brevis (FHB) - likely drive differences in how these muscles contribute to...
2.
Dutta S, Bhattacharya S, Harris H, Islam R, Bodas S, Polavaram N, et al.
Res Sq
. 2024 Jan;
PMID: 38168280
Resistance to the current Androgen Receptor Signaling Inhibitor (ARSI) therapies has led to higher incidences of therapy-induced neuroendocrine-like prostate cancer (t-NEPC). This highly aggressive subtype with predominant small cell-like characteristics...
3.
Kurihara T, Rowley M, Reischl S, Baker L, Kulig K
Acta Bioeng Biomech
. 2021 Nov;
22(4):23-29.
PMID: 34846029
Purpose: It is not well established how motion and muscle activation of the medial longitudinal arch (MLA) of the foot vary under different loading conditions. Intrinsic and extrinsic foot muscles...
4.
Alani M, Rowley M, Kang P, Chen S, Hirsch K, Seetharam A
Exp Clin Transplant
. 2019 Dec;
18(7):808-813.
PMID: 31830878
Objectives: Although no longer a contraindication to liver transplant, portal vein thrombosis may lead to longer operative time and complexities in venous reconstruction. Strategies to maintain preoperative patency include systemic...
5.
Lang D, Morris J, Rowley M, Torres M, Maksimovich V, Facchini P, et al.
J Biol Chem
. 2019 Aug;
294(40):14482-14498.
PMID: 31395658
Benzylisoquinoline alkaloids (BIAs) are a structurally diverse class of plant-specialized metabolites that have been particularly well-studied in the order Ranunculales. The -methyltransferases (NMTs) in BIA biosynthesis can be divided into...
6.
Jones P, Wilcoxen K, Rowley M, Toniatti C
J Med Chem
. 2015 Mar;
58(8):3302-14.
PMID: 25761096
Poly(ADP-ribose) polymerases (PARPs) are involved in DNA repair following damage by endogenous or exogenous processes. It has become clear over the past decade that inhibition of PARP in the context...
7.
Harper S, McCauley J, Rudd M, Ferrara M, DiFilippo M, Crescenzi B, et al.
ACS Med Chem Lett
. 2014 Jun;
3(4):332-6.
PMID: 24900473
A new class of HCV NS3/4a protease inhibitors containing a P2 to P4 macrocyclic constraint was designed using a molecular modeling-derived strategy. Building on the profile of previous clinical compounds...
8.
Rudd M, McIntyre C, Romano J, Butcher J, Holloway M, Bush K, et al.
Bioorg Med Chem Lett
. 2012 Oct;
22(23):7207-13.
PMID: 23084906
A series of macrocyclic compounds containing a cyclic constraint in the P2-P4 linker region have been discovered and shown to exhibit excellent HCV NS3/4a genotype 3a and genotype 1b R155K,...
9.
Rudd M, McCauley J, Romano J, Butcher J, Bush K, McIntyre C, et al.
Bioorg Med Chem Lett
. 2012 Oct;
22(23):7201-6.
PMID: 23021993
A series of macrocyclic compounds containing 2-substituted-quinoline moieties have been discovered and shown to exhibit excellent HCV NS3/4a genotype 3a and genotype 1b R155K mutant activity while maintaining the high...
10.
Di Francesco M, Avolio S, Dessole G, Koch U, Pompei M, Pucci V, et al.
Nucleosides Nucleotides Nucleic Acids
. 2012 Aug;
31(8):592-607.
PMID: 22908950
As part of an ongoing medicinal chemistry effort to identify novel nucleoside inhibitors of HCV NS5B polymerase, we report the discovery of a novel series of 2'-C-Methyl-ribose nucleoside derivatives bearing...