Stefan Guenther
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Explore the profile of Stefan Guenther including associated specialties, affiliations and a list of published articles.
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56
Citations
1421
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Recent Articles
1.
Kwon J, Kawase H, Mattonet K, Guenther S, Hahnefeld L, Shamsara J, et al.
Nat Commun
. 2025 Feb;
16(1):1448.
PMID: 39920161
Macrophages express numerous G protein-coupled receptors (GPCRs) that regulate adhesion, migration, and activation, but the function of orphan receptor GPRC5B in macrophages is unknown. Both resident peritoneal and bone marrow-derived...
2.
Bornhorst D, Hejjaji A, Steuter L, Woodhead N, Maier P, Gentile A, et al.
Nat Commun
. 2024 Aug;
15(1):7589.
PMID: 39217144
The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence that in zebrafish, the endocardium gives rise to and maintains a stable...
3.
Kumari P, Tarighi S, Fuchshuber E, Li L, Fernandez-Duran I, Wang M, et al.
Proc Natl Acad Sci U S A
. 2024 Jun;
121(25):e2409269121.
PMID: 38870055
Sirtuin 7 (SIRT7) is a member of the mammalian family of nicotinamide adenine dinucleotide (NAD)-dependent histone/protein deacetylases, known as sirtuins. It acts as a potent oncogene in numerous malignancies, but...
4.
Ribeiro da Silva A, Gunawan F, Boezio G, Faure E, Theron A, Avierinos J, et al.
Sci Adv
. 2024 May;
10(20):eadl0633.
PMID: 38748804
Biomechanical forces, and their molecular transducers, including key mechanosensitive transcription factor genes, such as , are required for cardiac valve morphogenesis. However, mutants fail to completely recapitulate the valveless phenotype...
5.
Schevenels G, Cabochette P, America M, Vandenborne A, De Grande L, Guenther S, et al.
Nature
. 2024 Apr;
628(8009):863-871.
PMID: 38570687
Vertebrate organs require locally adapted blood vessels. The gain of such organotypic vessel specializations is often deemed to be molecularly unrelated to the process of organ vascularization. Here, opposing this...
6.
Constanty F, Wu B, Wei K, Lin I, Dallmann J, Guenther S, et al.
bioRxiv
. 2024 Apr;
PMID: 38559277
Despite numerous advances in our understanding of zebrafish cardiac regeneration, an aspect that remains less studied is how regenerating cardiomyocytes invade, and eventually replace, the collagen-containing fibrotic tissue following injury....
7.
Yekelchyk M, Li X, Guenther S, Braun T
Methods Mol Biol
. 2024 Jan;
2752:245-257.
PMID: 38194039
During the last decade a wide range of single-cell and single-nucleus next-generation sequencing techniques have been developed, which revolutionized detection of rare cell populations, enabling creation of comprehensive cell atlases...
8.
Hu J, Leisegang M, Looso M, Drekolia M, Wittig J, Mettner J, et al.
Circ Res
. 2023 Oct;
133(10):842-857.
PMID: 37800327
Background: Advanced age is unequivocally linked to the development of cardiovascular disease; however, the mechanisms resulting in reduced endothelial cell regeneration remain poorly understood. Here, we investigated novel mechanisms involved...
9.
Glaser S, Brezski A, Baumgarten N, Klangwart M, Heumuller A, Maji R, et al.
Cell Rep
. 2023 Jul;
42(8):112824.
PMID: 37481725
Circular RNAs are generated by backsplicing and control cellular signaling and phenotypes. Pericytes stabilize capillary structures and play important roles in the formation and maintenance of blood vessels. Here, we...
10.
Moradi S, Guenther S, Soori S, Sharifi-Zarchi A, Kuenne C, Khoddami V, et al.
Stem Cell Rev Rep
. 2023 Jul;
19(7):2361-2377.
PMID: 37402099
Cells of the inner cell mass (ICM) acquire a unique ability for unlimited self-renewal during transition into embryonic stem cells (ESCs) in vitro, while preserving their natural multi-lineage differentiation potential....