Ruben Marin-Juez
Overview
Explore the profile of Ruben Marin-Juez including associated specialties, affiliations and a list of published articles.
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30
Citations
868
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0
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Recent Articles
1.
Gupta S, Bajwa G, El-Sammak H, Mattonet K, Gunther S, Looso M, et al.
Dev Biol
. 2025 Feb;
521:153-162.
PMID: 39983908
Myocardial infarction occurs when the coronary supply of oxygen and nutrients to part of the heart is interrupted. In contrast to adult mammals, adult zebrafish have a remarkable ability to...
2.
Wang Z, Mehra A, Wang Q, Gupta S, Ribeiro da Silva A, Juan T, et al.
Development
. 2024 Nov;
151(23).
PMID: 39612288
VEGFA administration has been explored as a pro-angiogenic therapy for cardiovascular diseases including heart failure for several years, but with little success. Here, we investigate a different approach to augment...
3.
Goumenaki P, Gunther S, Kikhi K, Looso M, Marin-Juez R, Stainier D
Nat Cardiovasc Res
. 2024 Sep;
3(9):1158-1176.
PMID: 39271818
The innate immune response is triggered rapidly after injury and its spatiotemporal dynamics are critical for regeneration; however, many questions remain about its exact role. Here we show that MyD88,...
4.
Chowdhury K, Lai S, Marin-Juez R
Methods Mol Biol
. 2022 Apr;
2475:297-312.
PMID: 35451767
Over the last decades, myocardial infarction and heart failure have accounted every year for millions of deaths worldwide. After a coronary occlusion, the lack of blood supply to downstream muscle...
5.
El-Sammak H, Yang B, Guenther S, Chen W, Marin-Juez R, Stainier D
Circ Res
. 2022 Mar;
130(7):1014-1029.
PMID: 35264012
Background: Ischemic heart disease following the obstruction of coronary vessels leads to the death of cardiac tissue and the formation of a fibrotic scar. In contrast to adult mammals, zebrafish...
6.
Tsedeke A, Allanki S, Gentile A, Jimenez-Amilburu V, Rasouli S, Guenther S, et al.
Dev Biol
. 2021 Apr;
476:259-271.
PMID: 33857482
Contrary to adult mammals, zebrafish are able to regenerate their heart after cardiac injury. This regenerative response relies, in part, on the endogenous ability of cardiomyocytes (CMs) to dedifferentiate and...
7.
Ding Y, Raterink R, Marin-Juez R, Veneman W, Egbers K, van den Eeden S, et al.
Sci Rep
. 2020 Jul;
10(1):11635.
PMID: 32669636
Tuberculosis is a highly infectious and potentially fatal disease accompanied by wasting symptoms, which cause severe metabolic changes in infected people. In this study we have compared the effect of...
8.
Fukuda R, Marin-Juez R, El-Sammak H, Beisaw A, Ramadass R, Kuenne C, et al.
EMBO Rep
. 2020 Jul;
21(8):e49752.
PMID: 32648304
Cardiac metabolism plays a crucial role in producing sufficient energy to sustain cardiac function. However, the role of metabolism in different aspects of cardiomyocyte regeneration remains unclear. Working with the...
9.
Hu W, Yang S, Shimada Y, Munch M, Marin-Juez R, Meijer A, et al.
BMC Genomics
. 2019 Nov;
20(1):878.
PMID: 31747871
Background: The function of Toll-like receptor 2 (TLR2) in host defense against pathogens, especially Mycobacterium tuberculosis (Mtb) is poorly understood. To investigate the role of TLR2 during mycobacterial infection, we...
10.
Marin-Juez R, El-Sammak H, Helker C, Kamezaki A, Mullapuli S, Bibli S, et al.
Dev Cell
. 2019 Nov;
51(4):503-515.e4.
PMID: 31743664
Defective coronary network function and insufficient blood supply are both cause and consequence of myocardial infarction. Efficient revascularization after infarction is essential to support tissue repair and function. Zebrafish hearts...