Stefan Bidula
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Explore the profile of Stefan Bidula including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
321
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Recent Articles
1.
Tammam M, Pereira F, Skellam E, Bidula S, Ganesan A, El-Demerdash A
Nat Prod Rep
. 2025 Feb;
PMID: 39989362
Covering: 2000-2023Cytochalasans are a fascinating class of natural products that possess an intricate chemical structure with a diverse range of biological activities. They are known for their complex chemical architectures...
2.
Bidula S, Piyasirananda W, Bielecka H, Bibic L, Beekman A, Stokes L
Purinergic Signal
. 2024 Oct;
PMID: 39436616
P2X7 is an emerging therapeutic target for several disorders and diseases due to its role in inflammatory signalling. This study aimed to exploit the unique chemical libraries of plants used...
3.
Johnson R, Wostear F, Solanki R, Steward O, Bradford A, Morris C, et al.
J Cell Sci
. 2024 Sep;
137(21).
PMID: 39301761
During ageing, the extracellular matrix of the aortic wall becomes more rigid. In response, vascular smooth muscle cells (VSMCs) generate enhanced contractile forces. Our previous findings demonstrate that VSMC volume...
4.
Johnson R, Solanki R, Wostear F, Ahmed S, Taylor J, Rees J, et al.
Br J Pharmacol
. 2023 Dec;
181(11):1576-1595.
PMID: 38044463
Background And Purpose: Decreased aortic compliance is a precursor to numerous cardiovascular diseases. Compliance is regulated by the rigidity of the aortic wall and the vascular smooth muscle cells (VSMCs)....
5.
Porubiakova O, Havlik J, Indu , Sedy M, Prepechalova V, Bartas M, et al.
Microbiol Spectr
. 2023 Jun;
11(4):e0164823.
PMID: 37358458
Noncanonical secondary structures in nucleic acids have been studied intensively in recent years. Important biological roles of cruciform structures formed by inverted repeats (IRs) have been demonstrated in diverse organisms,...
6.
Bidula S, Brazda V
Genes (Basel)
. 2023 Jan;
14(1).
PMID: 36672896
Non-B nucleic acids structures have arisen as key contributors to genetic variation in SARS-CoV-2. Herein, we investigated the presence of defining spike protein mutations falling within inverted repeats (IRs) for...
7.
Dobrovolna M, Brazda V, Warner E, Bidula S
J Med Virol
. 2022 Nov;
95(1):e28322.
PMID: 36400742
The current monkeypox virus (MPXV) strain differs from the strain arising in 2018 by 50+ single nucleotide polymorphisms (SNPs) and is mutating much faster than expected. The cytidine deaminase apolipoprotein...
8.
Bohalova N, Dobrovolna M, Brazda V, Bidula S
Biochimie
. 2021 Dec;
194:28-34.
PMID: 34942301
G-quadruplexes have important regulatory roles in the nuclear genome but their distribution and potential roles in mitochondrial DNA (mtDNA) are poorly understood. We analysed 11883 mtDNA sequences from 18 taxonomic...
9.
Bidula S, Nadzirin I, Cominetti M, Hickey H, Cullum S, Searcey M, et al.
Mol Pharmacol
. 2021 Oct;
101(1):33-44.
PMID: 34718224
The P2X4 receptor is a ligand-gated ion channel activated by extracellular ATP. P2X4 activity is associated with neuropathic pain, vasodilation, and pulmonary secretion and is therefore of therapeutic interest. The...
10.
Ghandhi L, Bidula S, Pask C, Lord R, McGowan P
ChemMedChem
. 2021 Jul;
16(20):3210-3221.
PMID: 34327861
This report highlights the synthesis and characterization of ten new bis(N-picolinamido)cobalt(II) complexes of the type [(L) CoX ] , whereby L=N-picolinamide ligand and X=diisothiocyanato (-NCS), dichlorido (-Cl) or diaqua (-OH...