A Ganesan
Overview
Explore the profile of A Ganesan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
125
Citations
2276
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tammam M, Pereira F, Skellam E, Bidula S, Ganesan A, El-Demerdash A
Nat Prod Rep
. 2025 Feb;
PMID: 39989362
Covering: 2000-2023Cytochalasans are a fascinating class of natural products that possess an intricate chemical structure with a diverse range of biological activities. They are known for their complex chemical architectures...
2.
Rothstein A, Chorghade M, Ibrahim H, Ganesan A, Erhardt P, Schnorrenberg G, et al.
J Med Chem
. 2025 Jan;
68(3):2095-2104.
PMID: 39879566
Data collected from scholars across twenty-three countries over the past decade (2010-2019) reveals a 40% decrease in financial support for medicinal chemistry projects. The decline is especially notable among projects...
3.
Chihomvu P, Ganesan A, Gibbons S, Woollard K, Hayes M
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201478
Phytochemicals have a long and successful history in drug discovery. With recent advancements in analytical techniques and methodologies, discovering bioactive leads from natural compounds has become easier. Computational techniques like...
4.
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer
Le M, Lu W, Tan X, Luo B, Yu T, Sun Y, et al.
J Med Chem
. 2024 Aug;
67(17):15586-15605.
PMID: 39196854
As histone modification enzymes, EZH2 mediates H3K27 trimethylation (H3K27me3), whereas LSD1 removes methyl groups from H3K4me1/2 and H3K9me1/2. Synergistic anticancer effects of combining inhibitors of these two enzymes are observed...
5.
Valmiki M, Teo S, de Resende P, Gibbons S, Ganesan A
Molecules
. 2024 Aug;
29(15).
PMID: 39125018
The tropical genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Ridl....
6.
Silva A, de Moraes D, do Carmo D, Gomes G, Ganesan A, Lopes R, et al.
J Fungi (Basel)
. 2023 Jul;
9(7).
PMID: 37504746
Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis. Nonetheless, their efficacy is limited by fungal resistance mechanisms, mainly the overexpression of efflux pumps. Consequently,...
7.
Sweet L, Daniels C, Xu X, Sunil T, Topal S, Chu X, et al.
Open Forum Infect Dis
. 2023 Jul;
10(7):ofad272.
PMID: 37476075
Background: Inappropriate antibiotic use in acute respiratory infections (ARIs) is a major public health concern; however, data for people with human immunodeficiency virus (PWH) are limited. Methods: The HIV Virtual...
8.
Nanavaty N, Walsh K, Boring B, Ganesan A, Carter-Sowell A, Mathur V
J Pain
. 2023 Feb;
24(7):1229-1239.
PMID: 36842734
Ostracism (ie, being ignored/excluded) is a form of social adversity that powerfully impacts health and well-being. While laboratory research indicates that experimentally manipulated experiences of ostracism impact pain, findings have...
9.
Bulut I, Lee A, Cevatemre B, Ruzic D, Belle R, Kawamura A, et al.
Cancers (Basel)
. 2022 Dec;
14(23).
PMID: 36497494
Defects in epigenetic pathways are key drivers of oncogenic cell proliferation. We developed a LSD1/HDAC6 multitargeting inhibitor (iDual), a hydroxamic acid analogue of the clinical candidate LSD1 inhibitor GSK2879552. iDual...
10.
Husain A, Ganesan A, Salah L, Kubat P, Ghazal B, Makhseed S
Chempluschem
. 2022 Nov;
87(11):e202200275.
PMID: 36420868
Tuning the amphiphilicity of (aza)phthalocyanine hydrophobic cores by introducing multiple polyethylene glycol (PEG) moieties with controlled orientations of their (non)peripheral positions is an innovative approach to fabricating water-soluble macrocyclic materials....