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Andrew Beekman

Explore the profile of Andrew Beekman including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Malbon A, Malbon A, Czopek A, Beekman A, Beekman A, Goddard Z, et al.
Biosci Rep . 2025 Jan; 45(2):157-170. PMID: 39869501
Approximately one in every 800 children is born with the severe aneuploid condition of Down syndrome (DS), a trisomy of chromosome 21. Low blood pressure (hypotension) is a common condition...
2.
Bidula S, Piyasirananda W, Bielecka H, Bibic L, Beekman A, Stokes L
Purinergic Signal . 2024 Oct; PMID: 39436616
 P2X7 is an emerging therapeutic target for several disorders and diseases due to its role in inflammatory signalling. This study aimed to exploit the unique chemical libraries of plants used...
3.
Piyasirananda W, Beekman A, Ganesan A, Bidula S, Stokes L
Mol Pharmacol . 2020 Dec; 99(2):163-174. PMID: 33334897
P2X7 is an important ligand-gated ion channel expressed in multiple immune cell populations. This study aimed to investigate the chemical requirements of triterpenoid glycosides within a new binding pocket to...
4.
Mills S, Howell L, Beekman A, Stokes L, Mueller A
Cell Signal . 2017 Oct; 42:88-96. PMID: 29050986
Cell migration towards a chemotactic stimulus relies on the re-arrangement of the cytoskeleton, which is triggered by activation of small G proteins RhoA, Rac1 and Cdc42, and leads to formation...