Stacy K Thomas
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Explore the profile of Stacy K Thomas including associated specialties, affiliations and a list of published articles.
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10
Citations
534
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Recent Articles
1.
Kim I, Diamond M, Yuan S, Kemp S, Kahn B, Li Q, et al.
Nat Commun
. 2024 Feb;
15(1):1532.
PMID: 38378697
Acquired resistance to immunotherapy remains a critical yet incompletely understood biological mechanism. Here, using a mouse model of pancreatic ductal adenocarcinoma (PDAC) to study tumor relapse following immunotherapy-induced responses, we...
2.
Wattenberg M, Coho H, Herrera V, Graham K, Stone M, Xue Y, et al.
Sci Immunol
. 2023 Nov;
8(89):eadj5097.
PMID: 37976347
Myeloid cells facilitate T cell immune evasion in cancer yet are pliable and have antitumor potential. Here, by cotargeting myeloid activation molecules, we leveraged the myeloid compartment as a therapeutic...
3.
Thomas S, Wattenberg M, Choi-Bose S, Uhlik M, Harrison B, Coho H, et al.
Nat Commun
. 2023 Oct;
14(1):6330.
PMID: 37816712
Although macrophages contribute to cancer cell dissemination, immune evasion, and metastatic outgrowth, they have also been reported to coordinate tumor-specific immune responses. We therefore hypothesized that macrophage polarization could be...
4.
Yuan S, Natesan R, Sanchez-Rivera F, Li J, Bhanu N, Yamazoe T, et al.
Cancer Discov
. 2020 Mar;
10(6):854-871.
PMID: 32188706
Epithelial plasticity, reversible modulation of a cell's epithelial and mesenchymal features, is associated with tumor metastasis and chemoresistance, leading causes of cancer mortality. Although different master transcription factors and epigenetic...
5.
Thomas S, Lee J, Beatty G
EBioMedicine
. 2020 Mar;
53:102662.
PMID: 32139180
Pancreatic ductal adenocarcinoma (PDAC) shows remarkable propensity to metastasize. This predilection to escape from the primary tumor is driven by paracrine and autocrine mechanisms that guide cancer cells through a...
6.
Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al.
Nature
. 2019 Mar;
567(7747):249-252.
PMID: 30842658
The liver is the most common site of metastatic disease. Although this metastatic tropism may reflect the mechanical trapping of circulating tumour cells, liver metastasis is also dependent, at least...
7.
Cruz A, Ramaswamy M, Ouyang C, Klebanoff C, Sengupta P, Yamamoto T, et al.
Nat Commun
. 2016 Dec;
7:13895.
PMID: 28008916
Mutations affecting the apoptosis-inducing function of the Fas/CD95 TNF-family receptor result in autoimmune and lymphoproliferative disease. However, Fas can also costimulate T-cell activation and promote tumour cell growth and metastasis....
8.
Fu Q, Fu T, Cruz A, Sengupta P, Thomas S, Wang S, et al.
Mol Cell
. 2016 Feb;
61(4):602-613.
PMID: 26853147
Fas (CD95, Apo-1, or TNFRSF6) is a prototypical apoptosis-inducing death receptor in the tumor necrosis factor receptor (TNFR) superfamily. While the extracellular domains of TNFRs form trimeric complexes with their...
9.
Klebanoff C, Scott C, Leonardi A, Yamamoto T, Cruz A, Ouyang C, et al.
J Clin Invest
. 2015 Dec;
126(1):318-34.
PMID: 26657860
Adoptive cell transfer (ACT) of purified naive, stem cell memory, and central memory T cell subsets results in superior persistence and antitumor immunity compared with ACT of populations containing more-differentiated...
10.
Ramirez-Peralta A, Stewart K, Thomas S, Setlow B, Chen Z, Li Y, et al.
J Bacteriol
. 2012 Apr;
194(13):3417-25.
PMID: 22522895
Bacillus subtilis isolates lacking the SpoVT protein, which regulates gene expression in developing forespores, gave spores that released their dipicolinic acid (DPA) via germinant receptor (GR)-dependent germination more rapidly than...