Srinivas Jayanthi
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Explore the profile of Srinivas Jayanthi including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
193
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Recent Articles
11.
Jayanthi S, Koppolu B, Nguyen K, Smith S, Felber B, Kumar T, et al.
Sci Rep
. 2017 Jul;
7(1):5360.
PMID: 28706183
Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS), modulate the functions of numerous cytokines. The aims of this multidisciplinary research were to characterize heparin binding to interleukin-12 (IL-12) and determine...
12.
Chintapalli S, Jayanthi S, Mallipeddi P, Gundampati R, Kumar T, van Rossum D, et al.
J Biol Chem
. 2016 Oct;
291(48):25133-25143.
PMID: 27758871
Previous research has indicated that long-chain fatty acids can bind myoglobin (Mb) in an oxygen-dependent manner. This suggests that oxy-Mb may play an important role in fuel delivery in Mb-rich...
13.
Henderson R, Gao F, Jayanthi S, Kight A, Sharma P, Goforth R, et al.
Biophys J
. 2016 Sep;
111(6):1151-1162.
PMID: 27653474
Chloroplast signal recognition particle (cpSRP) is a heterodimer composed of an evolutionarily conserved 54-kDa GTPase (cpSRP54) and a unique 43-kDa subunit (cpSRP43) responsible for delivering light-harvesting chlorophyll binding protein to...
14.
Morris J, Jayanthi S, Langston R, Daily A, Kight A, McNabb D, et al.
Protein Expr Purif
. 2016 May;
126:93-103.
PMID: 27235575
Purification of recombinant proteins constitutes a significant part of the downstream processing in biopharmaceutical industries. Major costs involved in the production of bio-therapeutics mainly depend on the number of purification...
15.
Mukherjee R, Beitle R, Jayanthi S, Kumar T, McNabb D
Biotechnol Prog
. 2016 May;
32(4):865-71.
PMID: 27162203
Interest in peptides as diagnostic and therapeutic materials require their manufacture via either a recombinant or synthetic route. This study examined the former, where a recombinant fusion consisting of an...
16.
Prudovsky I, Kacer D, Davis J, Shah V, Jayanthi S, Huber I, et al.
Biochemistry
. 2016 Feb;
55(7):1159-67.
PMID: 26836284
Fibroblast growth factor 1 (FGF1), a ubiquitously expressed pro-angiogenic protein that is involved in tissue repair, carcinogenesis, and maintenance of vasculature stability, is released from the cells via a stress-dependent...
17.
Gao F, Kight A, Henderson R, Jayanthi S, Patel P, Murchison M, et al.
J Biol Chem
. 2015 Apr;
290(25):15462-15474.
PMID: 25918165
Protein targeting is critical in all living organisms and involves a signal recognition particle (SRP), an SRP receptor, and a translocase. In co-translational targeting, interactions among these proteins are mediated...
18.
Jayanthi S, Kathir K, Rajalingam D, Furr M, Daily A, Thurman R, et al.
Biochim Biophys Acta
. 2014 Sep;
1844(12):2155-63.
PMID: 25224745
Fibroblast growth factor 1 (FGF1) is a heparin-binding proangiogenic protein. FGF1 lacks the conventional N-terminal signal peptide required for secretion through the endoplasmic reticulum (ER)-Golgi secretory pathway. FGF1 is released...
19.
Jayanthi S, Koppolu B, Smith S, Jalah R, Bear J, Rosati M, et al.
Protein Expr Purif
. 2014 Aug;
102:76-84.
PMID: 25123642
Interleukin-12 is a heterodimeric, pro-inflammatory cytokine that is a key driver of cell-mediated immunity. Clinical interest in IL-12 is significant due to its potent anti-tumor activity and efficacy in controlling...
20.
Koppolu B, Smith S, Ravindranathan S, Jayanthi S, Suresh Kumar T, Zaharoff D
Biomaterials
. 2014 Feb;
35(14):4382-9.
PMID: 24560459
Chitosan-based nano/microencapsulation is under increasing investigation for the delivery of drugs, biologics and vaccines. Despite widespread interest, the literature lacks a defined methodology to control chitosan particle size and drug/protein...