Sreyoshi Mitra
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Explore the profile of Sreyoshi Mitra including associated specialties, affiliations and a list of published articles.
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8
Citations
97
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Recent Articles
1.
van den Berg S, East S, Mitra S, Jansen L
Mol Biol Cell
. 2023 Mar;
34(5):br6.
PMID: 36989032
The centromere is a unique chromatin domain that links sister chromatids and forms the attachment site for spindle microtubules in mitosis. Centromere inheritance is largely DNA sequence-independent but strongly reliant...
2.
Mitra S, Srinivasan B, Jansen L
J Cell Biol
. 2020 Sep;
219(10).
PMID: 32931551
Chromosome segregation during cell division is driven by mitotic spindle attachment to the centromere region on each chromosome. Centromeres form a protein scaffold defined by chromatin featuring CENP-A, a conserved...
3.
Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al.
Nat Commun
. 2020 Jun;
11(1):2919.
PMID: 32522980
Replication and transcription of genomic DNA requires partial disassembly of nucleosomes to allow progression of polymerases. This presents both an opportunity to remodel the underlying chromatin and a danger of...
4.
Mitra S, Bodor D, David A, Abdul-Zani I, Mata J, Neumann B, et al.
Nat Commun
. 2020 Jan;
11(1):501.
PMID: 31980633
Centromeres are defined by a self-propagating chromatin structure based on stable inheritance of CENP-A containing nucleosomes. Here, we present a genetic screen coupled to pulse-chase labeling that allow us to...
5.
Srinivasan B, Zhou H, Mitra S, Skolnick J
Bioorg Med Chem
. 2016 Aug;
24(19):4750-4758.
PMID: 27567076
Peptide:N-glycanase (NGLY1) is an enzyme responsible for cleaving oligosaccharide moieties from misfolded glycoproteins to enable their proper degradation. Deletion and truncation mutations in this gene are responsible for an inherited...
6.
Srinivasan B, Marks H, Mitra S, Smalley D, Skolnick J
Biochem J
. 2016 May;
473(14):2165-77.
PMID: 27208174
The presence of latent activities in enzymes is posited to underlie the natural evolution of new catalytic functions. However, the prevalence and extent of such substrate and catalytic ambiguity in...
7.
Mitra S, Rai L, Chatterjee G, Sanyal K
Methods Mol Biol
. 2015 Nov;
1356:43-57.
PMID: 26519064
Chromatin immunoprecipitation (ChIP) is a widely used technique which can determine the in vivo association of a specific protein on a particular DNA locus in the genome. In this method...
8.
Mitra S, Gomez-Raja J, Larriba G, Dubey D, Sanyal K
PLoS Genet
. 2014 Apr;
10(4):e1004344.
PMID: 24762765
Specification of the centromere location in most eukaryotes is not solely dependent on the DNA sequence. However, the non-genetic determinants of centromere identity are not clearly defined. While multiple mechanisms,...