Soyeong Sim
Overview
Explore the profile of Soyeong Sim including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
504
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0
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Recent Articles
1.
Williams S, Sim S, Wolin S
RNA
. 2025 Jan;
31(3):369-381.
PMID: 39779213
Immune-mediated diseases are common in humans. The immune system is a complex host defense system that evolved to protect us from pathogens, but also plays an important role in homeostatic...
2.
Sim S, Hughes K, Chen X, Wolin S
Annu Rev Microbiol
. 2020 Jul;
74:387-407.
PMID: 32660384
Ro60 ribonucleoproteins (RNPs), composed of the ring-shaped Ro 60-kDa (Ro60) protein and noncoding RNAs called Y RNAs, are present in all three domains of life. Ro60 was first described as...
3.
Leng Y, Sim S, Magidson V, Wolin S
Nucleic Acids Res
. 2020 May;
48(12):6919-6930.
PMID: 32469055
Noncoding Y RNAs are abundant in animal cells and present in many bacteria. These RNAs are bound and stabilized by Ro60, a ring-shaped protein that is a target of autoantibodies...
4.
Belair C, Sim S, Kim K, Tanaka Y, Park I, Wolin S
J Cell Biol
. 2019 Jul;
218(8):2564-2582.
PMID: 31308215
A defining feature of embryonic stem cells (ESCs) is the ability to differentiate into all three germ layers. Pluripotency is maintained in part by a unique transcription network that maintains...
5.
Sim S, Wolin S
Microbiol Spectr
. 2018 Jul;
6(4).
PMID: 30006996
Y RNAs are noncoding RNAs (ncRNAs) that are present in most animal cells and also in many bacteria. These RNAs were discovered because they are bound by the Ro60 protein,...
6.
Greiling T, Dehner C, Chen X, Hughes K, Iniguez A, Boccitto M, et al.
Sci Transl Med
. 2018 Mar;
10(434).
PMID: 29593104
The earliest autoantibodies in lupus are directed against the RNA binding autoantigen Ro60, but the triggers against this evolutionarily conserved antigen remain elusive. We identified Ro60 orthologs in a subset...
7.
Belair C, Sim S, Wolin S
Chem Rev
. 2017 Oct;
118(8):4422-4447.
PMID: 29023106
Numerous surveillance pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective, and potentially harmful noncoding RNAs (ncRNAs). Because aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of...
8.
Eckwahl M, Sim S, Smith D, Telesnitsky A, Wolin S
Genes Dev
. 2015 Mar;
29(6):646-57.
PMID: 25792599
Although all retroviruses recruit host cell RNAs into virions, both the spectrum of RNAs encapsidated and the mechanisms by which they are recruited remain largely unknown. Here, we used high-throughput...
9.
Chen X, Sim S, Wurtmann E, Feke A, Wolin S
RNA
. 2014 Sep;
20(11):1715-24.
PMID: 25232022
Many bacteria encode an ortholog of the Ro60 autoantigen, a ring-shaped protein that is bound in animal cells to noncoding RNAs (ncRNAs) called Y RNAs. Studies in Deinococcus radiodurans revealed...
10.
Wolin S, Belair C, Boccitto M, Chen X, Sim S, Taylor D, et al.
RNA Biol
. 2013 Sep;
10(10):1602-8.
PMID: 24036917
Non-coding RNAs (ncRNAs) called Y RNAs are abundant components of both animal cells and a variety of bacteria. In all species examined, these ~100 nt RNAs are bound to the...