Sandra L Wolin
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Explore the profile of Sandra L Wolin including associated specialties, affiliations and a list of published articles.
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53
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2079
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Recent Articles
1.
Williams S, Sim S, Wolin S
RNA
. 2025 Jan;
31(3):369-381.
PMID: 39779213
Immune-mediated diseases are common in humans. The immune system is a complex host defense system that evolved to protect us from pathogens, but also plays an important role in homeostatic...
2.
Ortega J, Sasselli I, Boccitto M, Fleming A, Fortuna T, Li Y, et al.
Sci Adv
. 2023 Nov;
9(45):eadf7997.
PMID: 37948524
Amyotrophic lateral sclerosis and frontotemporal dementia patients with a hexanucleotide repeat expansion in (C9-HRE) accumulate poly-GR and poly-PR aggregates. The pathogenicity of these arginine-rich dipeptide repeats (R-DPRs) is thought to...
3.
Chen X, Wolin S
RNA
. 2023 Feb;
29(5):620-629.
PMID: 36781286
Transfer RNA fragments are proposed to regulate numerous processes in eukaryotes, including translation inhibition, epigenetic inheritance, and cancer. In the bacterium serovar Typhimurium, 5' tRNA halves ending in 2',3' cyclic...
4.
Wolin S
Mol Biol Cell
. 2021 Nov;
32(22):ae6.
PMID: 34793239
I am so very honored to receive the Women in Cell Biology Sandra K. Masur Senior Leadership Award from the American Society for Cell Biology (ASCB), particularly because many of...
5.
Williams S, Wolin S
Trends Mol Med
. 2021 Mar;
27(5):422-435.
PMID: 33722441
Although autoimmunity and autoimmune disease (AID) are relatively common, the repertoire of autoantigens is paradoxically very limited. Highly enriched in this autoantigen repertoire are nucleic acids and their binding proteins,...
6.
Hughes K, Chen X, Burroughs A, Aravind L, Wolin S
Cell Rep
. 2020 Dec;
33(12):108527.
PMID: 33357439
Many bacteria contain an RNA repair operon, encoding the RtcB RNA ligase and the RtcA RNA cyclase, that is regulated by the RtcR transcriptional activator. Although RtcR contains a divergent...
7.
Sim S, Hughes K, Chen X, Wolin S
Annu Rev Microbiol
. 2020 Jul;
74:387-407.
PMID: 32660384
Ro60 ribonucleoproteins (RNPs), composed of the ring-shaped Ro 60-kDa (Ro60) protein and noncoding RNAs called Y RNAs, are present in all three domains of life. Ro60 was first described as...
8.
Leng Y, Sim S, Magidson V, Wolin S
Nucleic Acids Res
. 2020 May;
48(12):6919-6930.
PMID: 32469055
Noncoding Y RNAs are abundant in animal cells and present in many bacteria. These RNAs are bound and stabilized by Ro60, a ring-shaped protein that is a target of autoantibodies...
9.
Seal R, Chen L, Griffiths-Jones S, Lowe T, Mathews M, OReilly D, et al.
EMBO J
. 2020 Feb;
39(6):e103777.
PMID: 32090359
Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous...
10.
Wolin S, Maquat L
Science
. 2019 Nov;
366(6467):822-827.
PMID: 31727827
The numerous quality control pathways that target defective ribonucleic acids (RNAs) for degradation play key roles in shaping mammalian transcriptomes and preventing disease. These pathways monitor most steps in the...