Soyeong Sim
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Explore the profile of Soyeong Sim including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
504
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Recent Articles
11.
Reed J, Sim S, Wolin S, Clancy R, Buyon J
J Immunol
. 2013 May;
191(1):110-6.
PMID: 23698747
Cardiac neonatal lupus (NL) is presumed to arise from maternal autoantibody targeting an intracellular ribonucleoprotein, Ro60, which binds noncoding Y RNA and only becomes accessible to autoantibodies during apoptosis. Despite...
12.
Wolin S, Sim S, Chen X
Trends Genet
. 2012 Apr;
28(7):306-13.
PMID: 22475369
Nuclear noncoding RNA (ncRNA) surveillance pathways play key roles in shaping the steady-state transcriptomes of eukaryotic cells. Defective and unneeded ncRNAs are primarily degraded by exoribonucleases that rely on protein...
13.
Sim S, Yao J, Weinberg D, Niessen S, Yates 3rd J, Wolin S
RNA
. 2011 Nov;
18(1):100-10.
PMID: 22114317
The Ro 60-kDa autoantigen, a ring-shaped RNA-binding protein, traffics between the nucleus and cytoplasm in vertebrate cells. In some vertebrate nuclei, Ro binds misfolded noncoding RNAs and may function in...
14.
Sim S, Wolin S
Wiley Interdiscip Rev RNA
. 2011 Aug;
2(5):686-99.
PMID: 21823229
All cells contain an enormous variety of ribonucleoprotein (RNP) complexes that function in diverse processes. Although the mechanisms by which many of these RNPs contribute to cell metabolism are well...
15.
Garcia E, Onafuwa-Nuga A, Sim S, King S, Wolin S, Telesnitsky A
J Virol
. 2009 Sep;
83(23):12526-34.
PMID: 19776129
Moloney murine leukemia virus (MLV) selectively encapsidates host mY1 and mY3 RNAs. These noncoding RNA polymerase III transcripts are normally complexed with the Ro60 and La proteins, which are autoantigens...
16.
Sim S, Weinberg D, Fuchs G, Choi K, Chung J, Wolin S
Mol Biol Cell
. 2009 Jan;
20(5):1555-64.
PMID: 19116308
The Ro autoantigen is a ring-shaped RNA-binding protein that binds misfolded RNAs in nuclei and is proposed to function in quality control. In the cytoplasm, Ro binds noncoding RNAs, called...
17.
Ko J, Han K, Kim Y, Sim S, Kim K, Lee S, et al.
Biochemistry
. 2007 Dec;
47(2):762-70.
PMID: 18092807
M1 RNA, the gene product of rnpB, is the catalytic subunit of RNase P in Escherichia coli. M1 RNA is transcribed from a proximal promoter as pM1 RNA, a precursor...
18.
Kim K, Sim S, Ko J, Lee Y
J Biol Chem
. 2005 Aug;
280(41):34667-74.
PMID: 16105832
M1 RNA, the catalytic subunit of Escherichia coli RNase P, is an essential ribozyme that processes the 5' leader sequence of precursor tRNAs. It is generated by the removal of...
19.
Kim K, Sim S, Ko J, Cho B, Lee Y
J Biochem
. 2005 Jan;
136(5):693-9.
PMID: 15632310
To gain insight into the mechanism by which the sequence at the rne-dependent site of substrate RNA affects the substrate specificity of Escherichia coli RNase E, we performed kinetic analysis...
20.
Sim S, Kim K, Lee Y
FEBS Lett
. 2002 Oct;
529(2-3):225-31.
PMID: 12372605
M1 RNA, the catalytic component of Escherichia coli RNase P, is derived from the 3'-end processing of precursor M1 RNA, a major transcript of the rnpB gene. In this study,...