Sotiria Tavoulari
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Explore the profile of Sotiria Tavoulari including associated specialties, affiliations and a list of published articles.
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21
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543
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Recent Articles
11.
Kunji E, Aleksandrova A, King M, Majd H, Ashton V, Cerson E, et al.
Biochim Biophys Acta
. 2016 Mar;
1863(10):2379-93.
PMID: 27001633
The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix, which are key transport steps for oxidative phosphorylation in eukaryotic organisms. The transport protein...
12.
Tavoulari S, Margheritis E, Nagarajan A, DeWitt D, Zhang Y, Rosado E, et al.
J Biol Chem
. 2015 Nov;
291(3):1456-71.
PMID: 26582198
In LeuT, a prokaryotic homolog of neurotransmitter transporters, Na(+) stabilizes outward-open conformational states. We examined how each of the two LeuT Na(+) binding sites contributes to Na(+)-dependent closure of the...
13.
Fenollar-Ferrer C, Stockner T, Schwarz T, Pal A, Gotovina J, Hofmaier T, et al.
Biochemistry
. 2014 Aug;
53(33):5444-60.
PMID: 25093911
Uptake of neurotransmitters by sodium-coupled monoamine transporters of the NSS family is required for termination of synaptic transmission. Transport is tightly regulated by protein-protein interactions involving the small cytoplasmic segments...
14.
Reyes N, Tavoulari S
J Gen Physiol
. 2011 Sep;
138(4):467-71.
PMID: 21911482
Transport proteins of the neurotransmitter sodium symporter (NSS) family regulate the extracellular concentration of several neurotransmitters in the central nervous system. The only member of this family for which atomic-resolution...
15.
Tavoulari S, Rizwan A, Forrest L, Rudnick G
J Biol Chem
. 2010 Dec;
286(4):2834-42.
PMID: 21115480
In ion-coupled transport proteins, occupation of selective ion-binding sites is required to trigger conformational changes that lead to substrate translocation. Neurotransmitter transporters, targets of abused and therapeutic drugs, require Na(+)...
16.
Tavoulari S, Forrest L, Rudnick G
J Neurosci
. 2009 Jul;
29(30):9635-43.
PMID: 19641126
Serotonin transporter (SERT) is the main target for widely used antidepressant agents. Several of these drugs, including imipramine, citalopram, sertraline, and fluoxetine (Prozac), bound more avidly to SERT in the...
17.
Tavoulari S, Frillingos S
J Mol Biol
. 2008 Jan;
376(3):681-93.
PMID: 18177889
We have examined the substrate selectivity of the melibiose permease (MelY) from Enterobacter cloacae in comparison with that of the lactose permease (LacY) from Escherichia coli. Both proteins catalyze active...
18.
Forrest L, Tavoulari S, Zhang Y, Rudnick G, Honig B
Proc Natl Acad Sci U S A
. 2007 Jul;
104(31):12761-6.
PMID: 17652169
The recent determination of the crystal structure of the leucine transporter from Aquifex aeolicus (aaLeuT) has provided significant insights into the function of neurotransmitter:sodium symporters. Transport by aaLeuT is Cl(-)...
19.
Karetsou Z, Martic G, Tavoulari S, Christoforidis S, Wilm M, Gruss C, et al.
FEBS Lett
. 2004 Nov;
577(3):496-500.
PMID: 15556635
Prothymosin alpha (ProTalpha) is a histone H1-binding protein that interacts with the transcription coactivator CREB-binding protein and potentiates transcription. Based on coimmunoprecipitation and mammalian two-hybrid assays, we show here that...
20.
Tavoulari S, Frillingos S, Karatza P, Messinis I, Seferiadis K
Hum Reprod
. 2004 Mar;
19(4):849-58.
PMID: 15016777
Background: Gonadotrophin surge-attenuating factor (GnSAF) is an as yet unidentified ovarian factor that acts on the pituitary to attenuate the pre-ovulatory LH surge. In a previous study, GnSAF bioactivity was...