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» Authors » Vasiliki Mavridou

Vasiliki Mavridou

Explore the profile of Vasiliki Mavridou including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 75
Followers 0
Related Specialties
Biology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Edmund R S Kunji
Sotiria Tavoulari
Martin S King
Chancievan Thangaratnarajah
Roger Springett
John Mifsud
Anna Chanou
Shujing Ding
Edmund Rs Kunji
Emmanuel Panteris
Published In
EMBO J
Nat Commun
Int J Mol Sci
Fish Shellfish Immunol Rep
Mol Metab
Affiliations
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Recent Articles
1.
Membrane potential stimulates ADP import and ATP export by the mitochondrial ADP/ATP carrier due to its positively charged binding site
Mavridou V, King M, Bazzone A, Springett R, Kunji E
Sci Adv . 2024 Nov; 10(44):eadp7725. PMID: 39485853
The mitochondrial adenosine 5'-diphosphate (ADP)/adenosine 5'-triphosphate (ATP) carrier imports ADP into the mitochondrion and exports ATP to the cell. Here, we demonstrate that 3.3 positive charges are translocated with the...
2.
Administration of probiotics affects metanauplii intestinal ultrastructure and offers resistance against a ssp induced oxidative stress response
Touraki M, Chanou A, Mavridou V, Tsertseli V, Tsiridi M, Panteris E
Fish Shellfish Immunol Rep . 2023 Sep; 5:100113. PMID: 37671319
The effects of ssp (Phdp) on immune responses and intestinal ultrastructure of following infection and their amelioration by the probiotic bacteria and were evaluated. Pathogen growth inhibition in coculture with...
3.
Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle
Mavridou V, King M, Tavoulari S, Ruprecht J, Palmer S, Kunji E
Nat Commun . 2022 Jun; 13(1):3585. PMID: 35739110
Mitochondrial ADP/ATP carriers import ADP into the mitochondrial matrix and export ATP to the cytosol to fuel cellular processes. Structures of the inhibited cytoplasmic- and matrix-open states have confirmed an...
4.
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
Tavoulari S, Schirris T, Mavridou V, Thangaratnarajah C, King M, Jones D, et al.
Mol Metab . 2022 Mar; 60:101469. PMID: 35278701
Objective: The mitochondrial pyruvate carrier (MPC) has emerged as a promising drug target for metabolic disorders, including non-alcoholic steatohepatitis and diabetes, metabolically dependent cancers and neurodegenerative diseases. A range of...
5.
A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Confers a Broad Nucleotide Specificity
King M, Tavoulari S, Mavridou V, King A, Mifsud J, Kunji E
Int J Mol Sci . 2020 Dec; 21(23. PMID: 33255957
is a clinically important eukaryotic parasite that causes the disease cryptosporidiosis, which manifests with gastroenteritis-like symptoms. The protist has mitosomes, which are organelles of mitochondrial origin that have only been...
6.
The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state
Tavoulari S, Thangaratnarajah C, Mavridou V, Harbour M, Martinou J, Kunji E
EMBO J . 2019 Apr; 38(10). PMID: 30979775
The mitochondrial pyruvate carrier (MPC) is critical for cellular homeostasis, as it is required in central metabolism for transporting pyruvate from the cytosol into the mitochondrial matrix. MPC has been...