Gary Rudnick
Overview
Explore the profile of Gary Rudnick including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
45
Citations
1906
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hellsberg E, Boytsov D, Chen Q, Niello M, Freissmuth M, Rudnick G, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(18):e2319384121.
PMID: 38652746
Clearance of serotonin (5-hydroxytryptamine, 5-HT) from the synaptic cleft after neuronal signaling is mediated by serotonin transporter (SERT), which couples this process to the movement of a Na ion down...
2.
Mayer F, Niello M, Bulling S, Zhang Y, Li Y, Kudlacek O, et al.
Neuropharmacology
. 2023 Sep;
240:109704.
PMID: 37703919
Mephedrone (4-methylmethcathinone) is a cathinone derivative that is recreationally consumed for its energizing and empathogenic effects. The stimulating properties are believed to arise from the ability of mephedrone to interact...
3.
Singh I, Seth A, Billesbolle C, Braz J, Rodriguiz R, Roy K, et al.
Cell
. 2023 May;
186(10):2160-2175.e17.
PMID: 37137306
The serotonin transporter (SERT) removes synaptic serotonin and is the target of anti-depressant drugs. SERT adopts three conformations: outward-open, occluded, and inward-open. All known inhibitors target the outward-open state except...
4.
Rudnick G
Neurochem Res
. 2021 Apr;
47(1):3-8.
PMID: 33929682
Baruch Kanner and this author have had parallel careers investigating neurotransmitter transporters. At multiple times during their careers, they have found themselves collaborating or competing, but always learning from each...
5.
Zhang Y, Uchendu S, Leone V, Bradshaw R, Sangwa N, Forrest L, et al.
Proc Natl Acad Sci U S A
. 2021 Mar;
118(10).
PMID: 33658361
The human GlyT1 glycine transporter requires chloride for its function. However, the mechanism by which Cl exerts its influence is unknown. To examine the role that Cl plays in the...
6.
Unger E, Keller J, Altermatt M, Liang R, Matsui A, Dong C, et al.
Cell
. 2020 Dec;
183(7):1986-2002.e26.
PMID: 33333022
Serotonin plays a central role in cognition and is the target of most pharmaceuticals for psychiatric disorders. Existing drugs have limited efficacy; creation of improved versions will require better understanding...
7.
8.
Rudnick G, Sandtner W
J Gen Physiol
. 2019 Oct;
151(11):1248-1264.
PMID: 31570504
Serotonin (5-hydroxytryptamine [5-HT]) is accumulated within nerve endings by the serotonin transporter (SERT), which terminates its extracellular action and provides cytoplasmic 5-HT for refilling of synaptic vesicles. SERT is the...
9.
Zhang Y, Tavoulari S, Sinning S, Aleksandrova A, Forrest L, Rudnick G
Proc Natl Acad Sci U S A
. 2018 Sep;
115(38):E8854-E8862.
PMID: 30181291
The coupled transport of ions and substrates allows transporters to accumulate substrates using the energy of transmembrane ion gradients and electrical potentials. During transport, conformational changes that switch accessibility of...
10.
Zhang Y, Turk B, Rudnick G
Proc Natl Acad Sci U S A
. 2016 May;
113(20):E2776-83.
PMID: 27140629
Serotonin transporter (SERT) is responsible for reuptake and recycling of 5-hydroxytryptamine (5-HT; serotonin) after its exocytotic release during neurotransmission. Mutations in human SERT are associated with psychiatric disorders and autism....