Silvina Bartesaghi
Overview
Explore the profile of Silvina Bartesaghi including associated specialties, affiliations and a list of published articles.
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29
Citations
734
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Recent Articles
1.
Galeano P, de Ceglia M, Mastrogiovanni M, Campanelli L, Medina-Vera D, Campolo N, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069333
This work aims to clarify the effect of dietary polyunsaturated fatty acid (PUFA) intake on the adult brain affected by amyloid pathology. McGill-R-Thy1-APP transgenic (Tg) rat and 5xFAD Tg mouse...
2.
4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification
Kiyuna L, Candido D, Bechara L, Jesus I, Ramalho L, Krum B, et al.
Eur Heart J
. 2023 Nov;
44(44):4696-4712.
PMID: 37944136
Background And Aims: Developing novel therapies to battle the global public health burden of heart failure remains challenging. This study investigates the underlying mechanisms and potential treatment for 4-hydroxynonenal (4-HNE)...
3.
Campolo N, Mastrogiovanni M, Mariotti M, Issoglio F, Estrin D, Hagglund P, et al.
J Biol Chem
. 2023 Jan;
299(3):102941.
PMID: 36702251
Glutamine synthetase (GS), which catalyzes the ATP-dependent synthesis of L-glutamine from L-glutamate and ammonia, is a ubiquitous and conserved enzyme that plays a pivotal role in nitrogen metabolism across all...
4.
Bartesaghi S, Garces G, Barrios E, Radi R
MedEdPublish (2016)
. 2022 Sep;
12:50.
PMID: 36168539
Exponential increases in the development of medical knowledge, the expansion of areas where medicine develops its activities, the emergence of new pathologies ( COVID-19), novel diagnostic methods and therapeutic strategies,...
5.
Folkes L, Bartesaghi S, Trujillo M, Wardman P, Radi R
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163717
The widespread interest in free radicals in biology extends far beyond the effects of ionizing radiation, with recent attention largely focusing on reactions of free radicals derived from peroxynitrite (i.e.,...
6.
Ott C, Tomasina F, Campolo N, Bartesaghi S, Mastrogiovanni M, Leyva A, et al.
Redox Biol
. 2021 Aug;
46:102106.
PMID: 34455147
Removal of moderately oxidized proteins is mainly carried out by the proteasome, while highly modified proteins are no longer degradable. However, in the case of proteins modified by nitration of...
7.
Folkes L, Bartesaghi S, Trujillo M, Wardman P, Radi R
Free Radic Res
. 2021 Jan;
55(2):141-153.
PMID: 33399021
Tyrosine is a critical component of many proteins and can be the subject of oxidative posttranslational modifications. Furthermore, the oxidation of tyrosine residues to phenoxyl radicals, sometimes quite stable, is...
8.
Campolo N, Issoglio F, Estrin D, Bartesaghi S, Radi R
Essays Biochem
. 2020 Feb;
64(1):111-133.
PMID: 32016371
Oxidative post-translational modification of proteins by molecular oxygen (O2)- and nitric oxide (•NO)-derived reactive species is a usual process that occurs in mammalian tissues under both physiological and pathological conditions...
9.
Pedron F, Bartesaghi S, Estrin D, Radi R, Zeida A
Free Radic Res
. 2018 Nov;
53(1):18-25.
PMID: 30468096
Proteins are main targets of oxidants in biological systems. This oxidation may occur in the protein backbone as well as in certain amino acid side chains, depending on the oxidant...
10.
Ferrer-Sueta G, Campolo N, Trujillo M, Bartesaghi S, Carballal S, Romero N, et al.
Chem Rev
. 2018 Feb;
118(3):1338-1408.
PMID: 29400454
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-controlled reaction of the free radicals superoxide (O) and nitric oxide (NO). In this review, we first analyze the...