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» Authors » Mauricio Mastrogiovanni

Mauricio Mastrogiovanni

Explore the profile of Mauricio Mastrogiovanni including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 32
Citations 281
Followers 0
Related Specialties
Biochemistry
General Medicine
Biology
Top 10 Co-Authors
Rafael Radi
Andres Trostchansky
Homero Rubbo
Madia Trujillo
Silvina Bartesaghi
Ari Zeida
Nicolas Campolo
Adrian Aicardo
Adriana Cassina
Ernesto Cuevasanta
Published In
Free Radic Biol Med
J Biol Chem
Proc Natl Acad Sci U S A
PLoS One
Arch Biochem Biophys
Affiliations
Soon will be listed here.
Recent Articles
1.
Tomato pomace-derived nitrated fatty acids: Synthesis and antiplatelet activity
Rodriguez L, Lagos F, Mastrogiovanni M, Flores A, Plaza A, Telleria F, et al.
Biomed Pharmacother . 2024 Jul; 177:117154. PMID: 39018868
This study investigates the antiplatelet properties of tomato pulp to combat cardiovascular diseases. Notably, it examines the formation of nitrated fatty acids (NO-FA) in tomato pomace, renowned for its potential...
2.
The Effect of Fat Intake with Increased Omega-6-to-Omega-3 Polyunsaturated Fatty Acid Ratio in Animal Models of Early and Late Alzheimer's Disease-like Pathogenesis
Galeano P, de Ceglia M, Mastrogiovanni M, Campanelli L, Medina-Vera D, Campolo N, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38069333
This work aims to clarify the effect of dietary polyunsaturated fatty acid (PUFA) intake on the adult brain affected by amyloid pathology. McGill-R-Thy1-APP transgenic (Tg) rat and 5xFAD Tg mouse...
3.
4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification
Kiyuna L, Candido D, Bechara L, Jesus I, Ramalho L, Krum B, et al.
Eur Heart J . 2023 Nov; 44(44):4696-4712. PMID: 37944136
Background And Aims: Developing novel therapies to battle the global public health burden of heart failure remains challenging. This study investigates the underlying mechanisms and potential treatment for 4-hydroxynonenal (4-HNE)...
4.
Photochemically-induced protein tyrosine nitration in vitro and in cellula by 5-methyl-1,4-dinitro-1H-imidazole (DNI): synthesis and biochemical characterization
Rios N, Aicardo A, Chavarria C, Ivagnes R, Mastrogiovanni M, Radi R, et al.
Free Radic Biol Med . 2023 Oct; 209(Pt 1):116-126. PMID: 37783316
The photochemical nitrating agent 5-methyl-1,4-dinitro-1H-imidazole (DNI) has been recently described as an effective tool for nitrating tyrosine residues in proteins under 390 nm irradiation (Long T. et al., 2021). Herein,...
5.
Disulfides form persulfides at alkaline pH leading to potential overestimations in the cold cyanolysis method
Benchoam D, Cuevasanta E, Semelak J, Mastrogiovanni M, Estrin D, Moller M, et al.
Free Radic Biol Med . 2023 Jul; 207:63-71. PMID: 37421993
It is well established that proteins and peptides can release sulfur under alkaline treatment, mainly through the β-elimination of disulfides with the concomitant formation of persulfides and dehydroalanine derivatives. In...
6.
Mitochondrial Peroxiredoxin 3 Is Rapidly Oxidized and Hyperoxidized by Fatty Acid Hydroperoxides
Cardozo G, Mastrogiovanni M, Zeida A, Viera N, Radi R, Reyes A, et al.
Antioxidants (Basel) . 2023 Feb; 12(2). PMID: 36829967
Human peroxiredoxin 3 (Prx3) is a thiol-based peroxidase responsible for the reduction of most hydrogen peroxide and peroxynitrite formed in mitochondria. Mitochondrial disfunction can lead to membrane lipoperoxidation, resulting in...
7.
Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
Campolo N, Mastrogiovanni M, Mariotti M, Issoglio F, Estrin D, Hagglund P, et al.
J Biol Chem . 2023 Jan; 299(3):102941. PMID: 36702251
Glutamine synthetase (GS), which catalyzes the ATP-dependent synthesis of L-glutamine from L-glutamate and ammonia, is a ubiquitous and conserved enzyme that plays a pivotal role in nitrogen metabolism across all...
8.
Corrigendum to "Fast and biphasic 8-nitroguanine production from guanine and peroxynitrite" [Free Radic. Biol. Med. 193 (2022) 474-484]
Sanchez A, Ibargoyen M, Mastrogiovanni M, Radi R, Keszenman D, Peluffo R
Free Radic Biol Med . 2022 Nov; 193(Pt 2):656. PMID: 36410073
No abstract available.
9.
Fast and biphasic 8-nitroguanine production from guanine and peroxynitrite
Sanchez A, Ibargoyen M, Mastrogiovanni M, Radi R, Keszenman D, Peluffo R
Free Radic Biol Med . 2022 Nov; 193(Pt 1):474-484. PMID: 36332879
Guanine (Gua), among purines, is a preferred oxidation/nitration target because of its low one-electron redox potential. The reactive oxygen/nitrogen species peroxynitrite (ONOO), produced in vivo by the reaction between nitric...
10.
Energy, protein and redox metabolism underlying adaptive responses in New Zealand versus North American Holstein cows in pasture-based dairy systems
Jorge-Smeding E, Carriquiry M, Casal A, Armand-Ugon D, Mastrogiovanni M, Trotschansky A, et al.
J Anim Physiol Anim Nutr (Berl) . 2022 Aug; 107(3):754-768. PMID: 36028944
This study explored the metabolic adaptions to grazing conditions of two Holstein genetic strains (GS; North American, NAH; New Zealand, NZH) in two feeding strategies (FS; restricted, P30, vs. maximised,...