Peter Wardman
Overview
Explore the profile of Peter Wardman including associated specialties, affiliations and a list of published articles.
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51
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1224
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Recent Articles
1.
Wardman P
Radiat Res
. 2023 Dec;
201(1):87-91.
PMID: 38050858
An earlier commentary (Wardman P, Radiat Res. 2020; 194:607-617) discussed possible chemical reaction pathways that might be involved in the differential responses of tissues to high- vs. low-dose-rate irradiation, focusing...
2.
Wardman P
Biomolecules
. 2023 Jul;
13(7).
PMID: 37509077
Numerous chemical probes have been used to measure or image oxidative, nitrosative and related stress induced by free radicals in biology and biochemistry. In many instances, the chemical pathways involved...
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4.
Folkes L, Bartesaghi S, Trujillo M, Wardman P, Radi R
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163717
The widespread interest in free radicals in biology extends far beyond the effects of ionizing radiation, with recent attention largely focusing on reactions of free radicals derived from peroxynitrite (i.e.,...
5.
Wardman P
Int J Radiat Biol
. 2022 Jan;
98(9):1399-1413.
PMID: 35073222
Purpose: Recent interest in understanding effects of high dose-rate ('FLASH') radiobiology has prompted a number of groups to model the chemical reactions that might be involved, either to estimate radiolytic...
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Folkes L, Bartesaghi S, Trujillo M, Wardman P, Radi R
Free Radic Res
. 2021 Jan;
55(2):141-153.
PMID: 33399021
Tyrosine is a critical component of many proteins and can be the subject of oxidative posttranslational modifications. Furthermore, the oxidation of tyrosine residues to phenoxyl radicals, sometimes quite stable, is...
8.
Wardman P
Radiat Res
. 2020 Dec;
194(6):607-617.
PMID: 33348369
Radiation chemists have been routinely using high-dose microsecond-pulsed irradiation for almost 60 years, involving many thousands of studies, in the technique of "pulse radiolysis". This involves dose rates broadly similar...
9.
Wardman P
Br J Radiol
. 2018 Jan;
92(1093):20170915.
PMID: 29303355
Nitroimidazoles have been extensively explored as hypoxic cell radiosensitizers but have had limited clinical success, with efficacy restricted by toxicity. However, they have proven clinically useful as probes for tumour...
10.
Close D, Wardman P
J Phys Chem A
. 2017 Dec;
122(1):439-445.
PMID: 29219315
Guanine (Guo) is generally accepted as the most easily oxidized DNA base when cells are subjected to ionizing radiation; calculations of the standard reduction potential of the guanyl radical, E(Guo/Guo)...