Shutsung Liao
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Explore the profile of Shutsung Liao including associated specialties, affiliations and a list of published articles.
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25
Citations
635
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Recent Articles
1.
Kokontis J, Lin H, Jiang S, Lin C, Fukuchi J, Hiipakka R, et al.
PLoS One
. 2014 Oct;
9(10):e109170.
PMID: 25271736
The majority of prostate cancer (PCa) patient receiving androgen ablation therapy eventually develop castration-resistant prostate cancer (CRPC). We previously reported that androgen treatment suppresses Skp2 and c-Myc through androgen receptor...
2.
Chuu C, Lin H, Ciaccio M, Kokontis J, Hause Jr R, Hiipakka R, et al.
Cancer Prev Res (Phila)
. 2012 May;
5(5):788-97.
PMID: 22562408
Caffeic acid phenethyl ester (CAPE) is a bioactive component derived from honeybee hive propolis. CAPE has been shown to have antimitogenic, anticarcinogenic, and other beneficial medicinal properties. Many of its...
3.
Chuu C, Kokontis J, Hiipakka R, Fukuchi J, Lin H, Lin C, et al.
Cancer Sci
. 2011 Jul;
102(11):2022-8.
PMID: 21781227
Androgen ablation therapy is the primary treatment for metastatic prostate cancer. However, this therapy is associated with several undesired side-effects, including increased risk of cardiovascular diseases. To study if termination...
4.
Peng L, Hiipakka R, Xie J, Kokontis J, Liao S, Peng D
J Cardiovasc Pharmacol
. 2011 May;
58(1):102-10.
PMID: 21558881
It has been previously observed that low-density lipoprotein receptor knockout (LDLR--/--) mice fed a Western-type diet without cholate and given the liver X receptor agonist T1317 develop a persistent and...
5.
Peng D, Hiipakka R, Xie J, Dai Q, Kokontis J, Reardon C, et al.
Br J Pharmacol
. 2011 Jan;
162(8):1792-804.
PMID: 21232031
Background And Purpose: Potent synthetic nonsteroidal liver X receptor (LXR) agonists like T0901317 induce triglyceridaemia and fatty liver, effects not observed with some natural and synthetic steroidal, relatively weak agonists...
6.
Lin S, Lin Y, Lin M, Kao Y, Wang R, Teng L, et al.
Eur J Med Chem
. 2010 Nov;
45(12):6068-76.
PMID: 21044810
A series of 3-O-acylated (-)-epigallocatechins were synthesized and their inhibition of steroid 5α-reductase was studied. They were prepared from the reaction of EGCG with tert-butyldimethylsilyl chloride followed by reductive cleavage...
7.
Guo J, Peng D, Dai Q, Liao S, Wright B, van Breemen R
J Chromatogr B Analyt Technol Biomed Life Sci
. 2010 Jul;
878(21):1885-8.
PMID: 20627826
The steroidal liver X receptor agonist, 3alpha,6alpha,24-trihydroxy-24,24-di(trifluoromethyl)-5beta-cholane (ATI-829) is a potential therapeutic agent for the treatment of atherosclerosis. A sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for the...
8.
Tang F, Kokontis J, Lin Y, Liao S, Lin A, Xiang J
J Biol Chem
. 2009 Sep;
284(47):32353-8.
PMID: 19723627
The male hormone androgen is a growth/survival factor for its target tissues or organs. Yet, the underlying mechanism is incompletely understood. Here, we report that androgen via p21 inhibits tumor...
9.
Peng D, Hiipakka R, Xie J, Reardon C, Getz G, Liao S
Atherosclerosis
. 2009 Jul;
208(1):126-33.
PMID: 19632679
The effects of liver X receptor (LXR) agonists on plasma lipid homeostasis, especially triglyceride metabolism are controversial. Here we examined the effect of long-term activation of LXR on plasma lipid...
10.
Chuu C, Chen R, Kokontis J, Hiipakka R, Liao S
Cancer Lett
. 2008 Nov;
275(1):86-92.
PMID: 18977589
The green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), inhibits the development and progression of prostate cancer in TRAMP mice and in men. We examined the effects of EGCG on LNCaP human prostate...