Shinichi Nishimura
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Explore the profile of Shinichi Nishimura including associated specialties, affiliations and a list of published articles.
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67
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1330
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Recent Articles
1.
Sasaki M, Nishimura S, Matsuyama A, Yoshida M
STAR Protoc
. 2023 Nov;
4(4):102675.
PMID: 37910512
Threonine deaminase catalyzes the first step of isoleucine biosynthesis from threonine. In this protocol, we describe the process of measuring the enzymatic activity of threonine deaminase in the fission yeast...
2.
Koyama H, Kashio A, Nishimura S, Takahashi H, Iwasaki S, Doi K, et al.
J Clin Med
. 2023 Jul;
12(13).
PMID: 37445325
Background: Few studies have reported on the etiology, severity, or device usage of unilateral sensorineural hearing loss (UHL) compared to bilateral hearing loss. Therefore, this study investigated the characteristics of...
3.
Matsuyama A, Hashimoto A, Nishimura S, Yoshida M
Sci Rep
. 2023 Jun;
13(1):9295.
PMID: 37291244
The expression of heterologous genes is an important technique in yeast genetics. In fission yeast, the leu1 and ura4 genes have been used mainly as selectable markers for heterologous expression....
4.
Sasaki M, Nishimura S, Yashiroda Y, Matsuyama A, Kakeya H, Yoshida M
iScience
. 2022 Dec;
25(12):105659.
PMID: 36505930
FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its...
5.
Chiu P, Nakamura Y, Nishimura S, Tabuchi T, Yashiroda Y, Hirai G, et al.
Sci Rep
. 2022 Oct;
12(1):17411.
PMID: 36302945
Microorganisms and plants produce siderophores, which function to transport environmental iron into cells as well as participate in cellular iron use and deposition. Their biological functions are diverse although their...
6.
Ueoka R, Sondermann P, Leopold-Messer S, Liu Y, Suo R, Bhushan A, et al.
Nat Chem
. 2022 Sep;
14(10):1193-1201.
PMID: 36064972
Host-associated bacteria are increasingly being recognized as underexplored sources of bioactive natural products with unprecedented chemical scaffolds. A recently identified example is the plant-root-associated marine bacterium Gynuella sunshinyii of the...
7.
Asai Y, Hiratsuka T, Ueda M, Kawamura Y, Asamizu S, Onaka H, et al.
ACS Chem Biol
. 2022 Jan;
17(1):207-216.
PMID: 35000376
Ferrichromes are a family of fungal siderophores with cyclic hexapeptide structures. Most fungi produce one or two ferrichrome-type siderophores. MF-347833 produces ferrichrome-like potent Trojan horse antifungal antibiotics ASP2397 and AS2488053,...
8.
Kanoh N, Terajima Y, Tanaka S, Terashima R, Nishiyama H, Nagasawa S, et al.
J Org Chem
. 2021 Nov;
86(23):16231-16248.
PMID: 34797655
A highly modular synthetic strategy for the heronamide C-type polyene macrolactams was established by synthesizing 8-deoxyheronamide C (). The developed strategy enabled not only the total synthesis of 8-deoxyheronamide C...
9.
Kanoh N, Terashima R, Nishiyama H, Terajima Y, Nagasawa S, Sasano Y, et al.
J Org Chem
. 2021 Nov;
86(23):16249-16258.
PMID: 34784214
16,17-Dihydroheronamide C () and -heronamide C (-) were designed as probes for the mode-of-action analysis of heronamide C (). These molecules were synthesized by utilizing a highly modular strategy developed...
10.
Amagasaki K, Nishimura S, Uchida T, Tatebayashi K, Nakaguchi H
Br J Neurosurg
. 2021 Oct;
38(4):863-866.
PMID: 34620013
Objective: The infrafloccular approach in microvascular decompression (MVD) surgery for hemifacial spasm (HFS) was investigated for the prevention of hearing complications. Methods: Retrospective analysis of 136 patients who underwent MVD...