Shin-Ichi Tomizawa
Overview
Explore the profile of Shin-Ichi Tomizawa including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
1140
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kuroha K, Dockal I, Radovic U, Nakajima K, Hoshi I, Matsuda S, et al.
Development
. 2025 Jan;
152(2).
PMID: 39745222
Cryptorchidism is the most frequent congenital defect in newborn males characterized by the absence of the testis from the scrotum. Approximately 90% of individuals with untreated bilateral cryptorchidism exhibit azoospermia...
2.
Ono M, Nakajima K, Tomizawa S, Shirakawa T, Okada I, Saitsu H, et al.
Gene Expr Patterns
. 2024 Nov;
54:119383.
PMID: 39510490
Smoc1 and Smoc2, members of the SPARC family of genes, encode signaling molecules downstream of growth factors such as the TGF-β, FGF, and PDGF families. Smoc1 has been implicated in...
3.
Tomizawa S, Fellows R, Ono M, Kuroha K, Dockal I, Kobayashi Y, et al.
Development
. 2024 Sep;
151(18).
PMID: 39222051
Male infertility can be caused by chromosomal abnormalities, mutations and epigenetic defects. Epigenetic modifiers pre-program hundreds of spermatogenic genes in spermatogonial stem cells (SSCs) for expression later in spermatids, but...
4.
Tomizawa S, Kuroha K, Ono M, Nakajima K, Ohbo K
Asian J Androl
. 2024 Aug;
27(1):37-43.
PMID: 39177410
Mouse spermatogenesis entails the maintenance and self-renewal of spermatogonial stem cells (SSCs), which require a complex web-like signaling network transduced by various cytokines. Although brain-derived neurotrophic factor (BDNF) is expressed...
5.
Naillat F, Saadeh H, Nowacka-Woszuk J, Gahurova L, Santos F, Tomizawa S, et al.
Clin Epigenetics
. 2021 Jun;
13(1):132.
PMID: 34183052
Background: Reproductive biology methods rely on in vitro follicle cultures from mature follicles obtained by hormonal stimulation for generating metaphase II oocytes to be fertilised and developed into a healthy...
6.
Takada Y, Yaman-Deveci R, Shirakawa T, Sharif J, Tomizawa S, Miura F, et al.
Development
. 2021 May;
148(10).
PMID: 33998651
Heterochromatin-related epigenetic mechanisms, such as DNA methylation, facilitate pairing of homologous chromosomes during the meiotic prophase of mammalian spermatogenesis. In pro-spermatogonia, de novo DNA methylation plays a key role in...
7.
Kobayashi Y, Tomizawa S, Ono M, Kuroha K, Minamizawa K, Natsume K, et al.
Development
. 2021 Mar;
148(8).
PMID: 33766931
During spermatogenesis, intricate gene expression is coordinately regulated by epigenetic modifiers, which are required for differentiation of spermatogonial stem cells (SSCs) contained among undifferentiated spermatogonia. We have previously found that...
8.
Miyake N, Takahashi H, Nakamura K, Isidor B, Hiraki Y, Koshimizu E, et al.
Am J Hum Genet
. 2019 Dec;
106(1):13-25.
PMID: 31839203
MN1 was originally identified as a tumor-suppressor gene. Knockout mouse studies have suggested that Mn1 is associated with craniofacial development. However, no MN1-related phenotypes have been established in humans. Here,...
9.
Nakajima K, Ono M, Radovic U, Dizdarevic S, Tomizawa S, Kuroha K, et al.
Dis Model Mech
. 2019 Sep;
12(11).
PMID: 31562139
Respiratory failure is a life-threatening problem for pre-term and term infants, yet many causes remain unknown. Here, we present evidence that whey acidic protein (WAP) four-disulfide core domain protease inhibitor...
10.
Tomizawa S, Kobayashi Y, Shirakawa T, Watanabe K, Mizoguchi K, Hoshi I, et al.
Development
. 2018 Dec;
145(23).
PMID: 30504434
The mammalian male germline is sustained by a pool of spermatogonial stem cells (SSCs) that can transmit both genetic and epigenetic information to offspring. However, the mechanisms underlying epigenetic transmission...