Shigeyuki Kitamura
Overview
Explore the profile of Shigeyuki Kitamura including associated specialties, affiliations and a list of published articles.
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Articles
93
Citations
965
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Recent Articles
1.
Tayama Y, Sugihara K, Sanoh S, Miyake K, Kitamura S, Ohta S
J Pharm Health Care Sci
. 2022 Dec;
8(1):31.
PMID: 36476607
Background: Allopurinol is used to treat hyperuricemia and gout. It is metabolized to oxypurinol by xanthine oxidase (XO), and aldehyde oxidase (AO). Allopurinol and oxypurinol are potent XO inhibitors that...
2.
Sakuragi Y, Takada H, Sato H, Kubota A, Terasaki M, Takeuchi S, et al.
Sci Total Environ
. 2021 Aug;
800:149374.
PMID: 34388645
Benzotriazole UV stabilizers (BUVSs) are added to various materials to prevent damage from UV-irradiation. Recently, there has been great concern regarding the endocrine-disrupting effects of exposure to microplastic-derivative BUVSs in...
3.
Sanoh S, Hanada H, Kashiwagi K, Mori T, Goto-Inoue N, Suzuki K, et al.
Aquat Toxicol
. 2020 Sep;
228:105623.
PMID: 32956954
Trace concentrations of a number of pharmaceutically active compounds have been detected in the aquatic environment in many countries, where they are thought to have the potential to exert adverse...
4.
Tsugoshi Y, Watanabe Y, Tanikawa Y, Inoue C, Sugihara K, Kojima H, et al.
Chem Biol Interact
. 2020 Jun;
327:109148.
PMID: 32511959
We investigated the inhibitory effects of 13 organophosphate esters (OPEs) and hydrolytic metabolites on the carboxylesterase activity of rat liver microsomes in vitro in order to examine whether there might...
5.
Fujino C, Watanabe Y, Sanoh S, Nakajima H, Uramaru N, Kojima H, et al.
Heliyon
. 2019 Sep;
5(9):e02466.
PMID: 31538121
In this study, we used reporter gene assays in COS-1 cells to examine the activation of rat pregnane X receptor (PXR), rat constitutive androstane receptor (CAR) and rat peroxisome-proliferator activated...
6.
Fujino C, Watanabe Y, Sanoh S, Hattori S, Nakajima H, Uramaru N, et al.
Food Chem Toxicol
. 2019 Sep;
133:110792.
PMID: 31472229
Parabens are widely used as preservatives in personal care products, medicines and foods, resulting in substantial human exposures, even though some harmful effects, such as endocrine-disrupting activity, have been reported....
7.
Kojima H, Takeuchi S, Sanoh S, Okuda K, Kitamura S, Uramaru N, et al.
Toxicology
. 2018 Dec;
413:48-55.
PMID: 30582956
Several bisphenol A (BPA) analogues have been detected in environmental samples, foodstuffs, and/or human biological samples, and there is concern regarding their potential endocrine-disrupting effects. In this study, we characterized...
8.
Kitamura S
Yakugaku Zasshi
. 2018 May;
138(5):693-713.
PMID: 29710015
The endocrine-disrupting activities of various environmental chemicals are metabolically activated. For example, diphenyls, styrene oligomers, chalcones, trans-stilbene and 2-nitrofluorene are not estrogens, but after incubation with liver microsomes, their metabolites...
9.
Takaoka N, Sanoh S, Okuda K, Kotake Y, Sugahara G, Yanagi A, et al.
Biochem Pharmacol
. 2018 Apr;
154:28-38.
PMID: 29678521
As aldehyde oxidase (AOX) plays an emerging role in drug metabolism, understanding its significance for drug-drug interactions (DDI) is important. Therefore, we tested 10 compounds for species-specific and substrate-dependent differences...
10.
Fujimoto N, Kitamura S, Uramaru N, Miyagawa S, Iguchi T
Toxicol Lett
. 2018 Jan;
286:48-53.
PMID: 29357290
There have been many concerns about the possible adverse effects of thyroid hormone-disrupting chemicals in the environment. Because thyroid hormones are essential for regulating the growth and differentiation of many...