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Xenobiotica; the Fate of Foreign Compounds in Biological Systems

Xenobiotica is a renowned scientific journal that focuses on the study of foreign compounds in biological systems. It provides a platform for researchers to explore the fate, metabolism, and toxicology of xenobiotics, including drugs, environmental pollutants, and other foreign substances. With its multidisciplinary approach, Xenobiotica offers valuable insights into the interactions between these compounds and living organisms, contributing to advancements in pharmacology, toxicology, and environmental sciences.

Details
Abbr. Xenobiotica
Publisher Informa Healthcare
Start 1971
End Continuing
Frequency Monthly
p-ISSN 0049-8254
e-ISSN 1366-5928
Country United Kingdom
Language English
Specialties Biochemistry
Toxicology
Metrics
h-index / Ranks: 3747 89
SJR / Ranks: 10567 387
CiteScore / Ranks: 7049 3.80
JIF / Ranks: 5564 1.8
Recent Articles
1.
Ahad A, Raish M, BinJardan Y, Al-Mohizea A, Al-Jenoobi F
Xenobiotica . 2025 Mar; :1-13. PMID: 40078049
1. The goal of current investigation was to develop eugenol fortified fisetin nano-invasomes. Fisetin loaded invasomes were prepared using thin film hydration procedure and evaluated for various parameters. Additionally, the...
2.
Yanovskaya E, Frelikh G, Lakeev A, Smolyakova V, Chernysheva G
Xenobiotica . 2025 Feb; :1-33. PMID: 39964734
IBP (2,6-diisobornyl-4-methylphenol) is a camphene derivative with unique pharmacological properties and low toxicity. It exhibits pronounced antioxidant and membrane-protective effects, making it a promising cardio- and neuroprotector.The aim of the...
3.
Li J, Sun S, Li Y, Tian M, Li X, Ren S, et al.
Xenobiotica . 2025 Feb; :1-14. PMID: 39932394
The Nrf2 signalling pathway is crucial for cellular defense against oxidative stress and xenobiotic toxicity, highlighting its importance in both human health and environmental responses.This review focuses on the dual...
4.
Tagawa K, Maruo Y
Xenobiotica . 2025 Jan; 1-8. PMID: 39815789
Dolutegravir (DTG) is a key drug used to treat human immunodeficiency virus type-1 (HIV-1) infections. Adverse events (AEs) of DTG treatment, including headache, anxiety, depression, insomnia, and abnormal dreams, are...
5.
Farris F, Awaness A, Su J
Xenobiotica . 2025 Jan; 55(1):4-15. PMID: 39792020
A four-compartment model is presented that simulates inorganic mercury [Hg(II)] pharmacokinetics in blood, tissue, and excreta over a 70-day period. Simulations are validated against data collected from five human subjects,...
6.
Tsyplakova N, Ismailos G, Karalis V
Xenobiotica . 2025 Jan; 55(1):25-36. PMID: 39764686
Idiopathic Pulmonary Fibrosis (IPF) is a chronic respiratory disorder for which pirfenidone is the recommended first-line anti-fibrotic treatment. While pirfenidone has demonstrated efficacy in slowing the progression of IPF, its...
7.
Gao Y, Ma J
Xenobiotica . 2025 Jan; 55(1):16-24. PMID: 39754510
Polymorphisms in genes related to drug-metabolising enzymes may affect tacrolimus exposure. This study aimed to assess the influence of , , and polymorphisms on tacrolimus pharmacokinetics and outcomes in allogeneic...
8.
Kobayashi T, Sato H, Akamine Y, Fukushi Y, Takahashi N, Miura M
Xenobiotica . 2024 Dec; 55(1):37-42. PMID: 39668710
The aim of this study was to investigate the effects of renal function and polymorphism on the drug interaction between venetoclax and fluconazole in thirty acute myeloid leukaemia patients.The area...
9.
Waring R, Mitchell S
Xenobiotica . 2024 Dec; 55(1):1-3. PMID: 39668708
No abstract available.
10.
Shaik I, Chaphekar N, Vasudevan V, Alshabi A, AlOwaifeer A, Zhao W, et al.
Xenobiotica . 2024 Nov; 54(10):821-830. PMID: 39584456
Intramuscular (250 mg once weekly) or subcutaneous (275 mg once weekly) injections of 17-hydroxyprogesterone caproate (17-OHPC) has been utilised to prevent recurent spontaneous preterm birth in pregnant women with a...