Sheryl A Lazarus
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Explore the profile of Sheryl A Lazarus including associated specialties, affiliations and a list of published articles.
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14
Citations
340
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Recent Articles
1.
Bina M, Wyss P, Lazarus S, Shah S, Ren W, Szpankowski W, et al.
Genomics
. 2008 Dec;
93(4):314-22.
PMID: 19084590
We developed a computational model to explore the hypothesis that regulatory instructions are context dependent and conveyed through specific 'codes' in human genomic DNA. We provide examples of correlation of...
2.
Wyss P, Lazarus S, Bina M
Methods Mol Biol
. 2006 Aug;
338:135-52.
PMID: 16888356
A major challenge in systems biology is to discover and reconstruct the cis-regulatory networks through which the expression of genes is controlled. Even though a variety of sequences have been...
3.
Bina M, Wyss P, Ren W, Szpankowski W, Thomas E, Randhawa R, et al.
Genomics
. 2004 Nov;
84(6):929-40.
PMID: 15533710
Central to reconstruction of cis-regulatory networks is identification and classification of naturally occurring transcription factor-binding sites according to the genes that they control. We have examined salient characteristics of 9-mers...
4.
5.
Lazarus S, Garg M
Int J Food Sci Nutr
. 2004 Jun;
55(3):249-56.
PMID: 15223602
Epidemiological data have reported an inverse relationship between the consumption of tomatoes and tomato products and the risk of cardiovascular disease. However, the mechanism(s) by which tomatoes may reduce cardiovascular...
6.
Rios L, Gonthier M, Remesy C, Mila I, Lapierre C, Lazarus S, et al.
Am J Clin Nutr
. 2003 Mar;
77(4):912-8.
PMID: 12663291
Background: Proanthocyanidins, the most abundant polyphenols in chocolate, are not depolymerized in the stomach and reach the small intestine intact, where they are hardly absorbed because of their high molecular...
7.
Zhu Q, Hammerstone J, Lazarus S, Schmitz H, Keen C
J Agric Food Chem
. 2003 Jan;
51(3):828-33.
PMID: 12537465
Cocoa flavanols and procyanidins have numerous biological activities. It is known that (-)-epicatechin, (+)-catechin, epicatechin-(4beta-8)-epicatechin (dimer B2), and epicatechin-(4beta-6)-epicatechin (dimer B5) are unstable at physiologic pH, degrading almost completely within...
8.
Rios L, Bennett R, Lazarus S, Remesy C, Scalbert A, Williamson G
Am J Clin Nutr
. 2002 Oct;
76(5):1106-10.
PMID: 12399286
Background: Polyphenolic procyanidins are abundant flavonoid polymers in Western diets. In vitro biological activity has been reported for these compounds, but activity in vivo depends on the amount and chemical...
9.
Ottaviani J, Carrasquedo F, Keen C, Lazarus S, Schmitz H, Fraga C
Arch Biochem Biophys
. 2002 Oct;
406(2):203-8.
PMID: 12361708
The flavan-3-ols (-)-epicatechin (epicatechin) and (+)-catechin (catechin) and their related oligomers (procyanidins) isolated from cocoa were assayed for their capacity to inhibit the UVC-mediated formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine (oxo(8)dG) in calf...
10.
Holt R, Lazarus S, Sullards M, Zhu Q, Schramm D, Hammerstone J, et al.
Am J Clin Nutr
. 2002 Sep;
76(4):798-804.
PMID: 12324293
Background: Epidemiologic studies have linked flavonoid-rich foods with a reduced risk of cardiovascular mortality. Some cocoas are flavonoid-rich and contain the monomeric flavanols (-)-epicatechin and (+)-catechin and oligomeric procyanidins formed...