Sherif F Hammad
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Explore the profile of Sherif F Hammad including associated specialties, affiliations and a list of published articles.
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31
Citations
109
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Recent Articles
21.
Elgiushy H, Mohamed S, Taha H, Sawaf H, Hassan Z, Abou-Taleb N, et al.
Bioorg Chem
. 2022 Feb;
120:105646.
PMID: 35134645
A new series of sixteen new 2-arylamino-5,7-disubstituted-N-aryl-pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives was designed and synthesized. The antitumor activities of the new compounds were initially screened through the developmental therapeutics program at NCI-USA 60...
22.
Elgiushy H, Abou-Taleb N, Holz G, Chepurny O, Pirmettis I, Kakabakos S, et al.
Bioorg Chem
. 2021 Jun;
114:105079.
PMID: 34174633
Corticotrophin releasing factor receptor-1 (CRFR1) is a potential target for treatment of depression and anxiety through modifying stress response. A series of new thiazolo[4,5-d]pyrimidine derivatives were designed, prepared and biologically...
23.
Mohamed S, Elgiushy H, Taha H, Hammad S, Abou-Taleb N, Abouzid K, et al.
Bioorg Med Chem
. 2020 Aug;
28(17):115633.
PMID: 32773088
New thiazolo[4,5-d]pyrimidine analogues were synthesized and biologically assessed in-vitro for their antineoplastic activity. The growth inhibitory effects of these compounds were assessed through the National Cancer Institute-United States of America...
24.
Abu-Zaied M, Hammad S, Halaweish F, Elgemeie G
ACS Omega
. 2020 Jun;
5(24):14645-14655.
PMID: 32596602
The synthesis and antiviral screening of the first reported series of pyridine- and pyrimidine-based thioglycoside phosphoramidates are herein reported. They were prepared through two synthetic steps: The first step is...
25.
Almeer R, Hammad S, Leheta O, Abdel Moneim A, Amin H
Int J Mol Sci
. 2019 Nov;
20(22).
PMID: 31718011
The present study aimed to test the anti-inflammatory and xanthine oxidase inhibitory activities of two synthesized molecules and compare them to routinely prescribed nonsteroidal anti-inflammatory drugs (NSAIDs), such as diclofenac...
26.
Abdelsalam E, Zaghary W, Amin K, A Abou Taleb N, Mekawey A, Eldehna W, et al.
Bioorg Chem
. 2019 May;
89:102985.
PMID: 31121559
derivatives of benzo[g]indazole 5a, b, benzo[h]quinazoline 7, 12a-c, 13a-c and 15a-c and benzo[h]quinoline 17a-c and 19a-c were synthesized from 6-methoxy-3,4-dihydronaphthalen-1(2H)-one (1). Anticancer activity of all the synthesized compounds was evaluated...
27.
Baker M, Hammad S, Belal T
Drug Dev Ind Pharm
. 2019 Apr;
45(7):1111-1119.
PMID: 30929537
This study describes a simple, sensitive, specific and generic HPLC-DAD method for simultaneous determination of four drugs prescribed for treatment of Hepatitis C Virus (HCV) infection. Investigated drugs include daclatasvir...
28.
Hammad S, Masoud D, Elgemeie G, Jones P
Acta Crystallogr E Crystallogr Commun
. 2018 Jun;
74(Pt 6):853-856.
PMID: 29951244
In the racemic title compound, CHNOS, the sulfur atom is attached equatorially to the sugar ring with unequal S-C bonds, .: S-C = 1.808 (2) and S-C = 1.770 (2) ...
29.
Masoud D, Hammad S, Elgemeie G, Jones P
Acta Crystallogr E Crystallogr Commun
. 2017 Nov;
73(Pt 11):1751-1754.
PMID: 29152366
In the title compound, CHNOS, the C-S bond lengths are unequal, with S-C = 1.8016 (15) Å and S-C = 1.7723 (13) Å. The hydro-philic glucose residues lie in the...
30.
Bedewy W, Liao H, Abou-Taleb N, Hammad S, Nasr T, Pei D
Org Biomol Chem
. 2017 May;
15(21):4540-4543.
PMID: 28517007
Cyclic peptides are capable of binding and modulating challenging drug targets including protein-protein interactions. However, their lack of membrane permeability prevents their application against intracellular targets. In this study, we...