Sherif F Hammad
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Explore the profile of Sherif F Hammad including associated specialties, affiliations and a list of published articles.
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31
Citations
109
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Recent Articles
11.
Khatab H, Hammad S, El-Fakharany E, Hashem A, El-Helw E
Sci Rep
. 2023 Sep;
13(1):15093.
PMID: 37699954
In this study, we aimed to develop hybrid antitumor compounds by synthesizing and characterizing novel N-substituted acrididine-1,8-dione derivatives, designed as hybrids of phthalimide and acridine-1,8-diones. We employed a three-step synthetic...
12.
Ahmed M, El-Haggar R, Almalki A, Abdullah O, El Hassab M, Masurier N, et al.
Arch Pharm (Weinheim)
. 2023 Jul;
356(9):e2300244.
PMID: 37404064
Merging isatin and arylhydrazone moieties constitutes an efficient strategy to access new potential anticancer derivatives. Consequently, 14 hydrazone-isatin derivatives were synthesized and evaluated for their antiproliferative activity against the NCI-60...
13.
Anifowose L, Paimo O, Adegboyega F, Ogunyemi O, Akano R, Hammad S, et al.
In Silico Pharmacol
. 2023 Jun;
11(1):15.
PMID: 37323538
Graphical Abstract: A structure-based virtual screening and simulation of phytochemicals in the active pocket of AKT 1 and 2 isoforms.
14.
Edrees F, Draz M, Saad A, Hammad S, Mohamed H
Sci Rep
. 2023 May;
13(1):8797.
PMID: 37258556
Molnupiravir (MPV) is the first direct-acting oral antiviral drug that effectively decreases nasopharyngeal infections with SARS-CoV-2 virus. The stability of MPV was tested by subjecting the drug to various stress...
15.
Tawfik N, Teiama M, Iskandar S, Osman A, Hammad S
Int J Nanomedicine
. 2023 Mar;
18:1219-1243.
PMID: 36937550
Background: Thalidomide (THD) and its analogues were recently reported as a promising treatment for different types of solid tumors due to their antiangiogenic effect. Methods: In this work, we synthesized...
16.
El-Haggar R, Hammad S, Alsantali R, Alrooqi M, El Hassab M, Masurier N, et al.
Bioorg Chem
. 2022 Oct;
129:106172.
PMID: 36182865
The overexpression of EGFR has been recognized as the driver mechanism in the development of several human malignancies and the clinical use of EGFR inhibitors currently constitutes the standard of...
17.
Rashed S, Hammad S, Eldakak M, Khalil I, Osman A
J Pharm Sci
. 2022 Sep;
112(1):213-224.
PMID: 36087776
Phycocyanin (C-PC) is a constitutive chromoprotein of Arthrospira platensis, which exhibits promising efficacy against different types of cancer. In this study, we cleaved C-PC's chromophore phycocyanobilin (PCB) and demonstrated its...
18.
Khayat M, Zarka M, El-Telbany D, El-Halawany A, Kutbi H, Elkhatib W, et al.
Sci Rep
. 2022 Sep;
12(1):15235.
PMID: 36075939
Resveratrol (RSV), a non-flavonoid stilbene polyphenol, possesses anti-carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN NPs) have been utilized successfully in delivery of variant therapeuticals by...
19.
Abdelsalam E, Abd El-Hafeez A, Eldehna W, El Hassab M, Marzouk H, Elaasser M, et al.
J Enzyme Inhib Med Chem
. 2022 Aug;
37(1):2265-2282.
PMID: 36000167
New series of thiazolyl-pyrazoline derivatives (, and ) have been synthesised and assessed for their potential EGFR and VEGFR-2 inhibitory activities. Compounds and exerted potent and selective inhibitory activity towards...
20.
Abu-Zaied M, Elgemeie G, Halaweish F, Hammad S
Nucleosides Nucleotides Nucleic Acids
. 2022 Jun;
41(9):851-877.
PMID: 35737369
A novel series of pyridine, cytosine, and uracil thioglycoside analogs ( and respectively) and their corresponding phosphoramidates ( and respectively) were synthesized and assessed for their antiviral inhibitory activities in...