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Shaun W Jackson

Explore the profile of Shaun W Jackson including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 1422
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Recent Articles
1.
Thouvenel C, Tipton C, Yamazaki Y, Zhang T, Rylaarsdam S, Hom J, et al.
J Clin Immunol . 2025 Jan; 45(1):66. PMID: 39812873
Reduced function or hypomorphic variants in recombination-activating genes (RAG) 1 or 2 result in a broad clinical phenotype including common variable immunodeficiency (CVID) and even adult-onset disease. Milder RAG variants...
2.
Danaher P, Hasle N, Nguyen E, Roberts J, Rosenwasser N, Rickert C, et al.
Sci Transl Med . 2024 Nov; 16(775):eadl1666. PMID: 39602512
Children with systemic lupus erythematosus (SLE) are at increased risk of developing kidney disease, termed childhood-onset lupus nephritis (cLN). Single-cell transcriptomics of dissociated kidney tissue has advanced our understanding of...
3.
Bodansky A, Yu D, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green D, et al.
J Clin Invest . 2024 May; 134(13). PMID: 38753445
Given the global surge in autoimmune diseases, it is critical to evaluate emerging therapeutic interventions. Despite numerous new targeted immunomodulatory therapies, comprehensive approaches to apply and evaluate the effects of...
4.
Liu S, Lagos J, Shumlak N, Largent A, Lewis S, Holder U, et al.
J Exp Med . 2024 Mar; 221(4). PMID: 38442270
Genome-wide association studies in systemic lupus erythematosus (SLE) have linked loss-of-function mutations in phagocytic NADPH oxidase complex (NOX2) genes, including NCF1 and NCF2, to disease pathogenesis. The prevailing model holds...
5.
Bodansky A, Yu D, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green D, et al.
medRxiv . 2024 Jan; PMID: 38196603
The prevalence and burden of autoimmune and autoantibody mediated disease is increasing worldwide, yet most disease etiologies remain unclear. Despite numerous new targeted immunomodulatory therapies, comprehensive approaches to apply and...
6.
Danaher P, Hasle N, Nguyen E, Hayward K, Rosenwasser N, Alpers C, et al.
bioRxiv . 2023 Nov; PMID: 38014158
Children with systemic lupus erythematosus (SLE) are at increased risk of developing kidney disease, termed childhood-onset lupus nephritis (cLN). Single cell transcriptomics of dissociated kidney tissue has advanced our understanding...
7.
Largent A, Lambert K, Chiang K, Shumlak N, Liggitt D, Oukka M, et al.
Sci Transl Med . 2023 Jul; 15(703):eade7028. PMID: 37406138
Heterozygous signal transducer and activator of transcription 1 () gain-of-function (GOF) mutations promote a clinical syndrome of immune dysregulation characterized by recurrent infections and predisposition to humoral autoimmunity. To gain...
8.
Jackson S, Rovin B
Kidney Int . 2023 Apr; 103(5):824-826. PMID: 37085253
No abstract available.
9.
Pemberton S, Jackson S
Arthritis Rheumatol . 2023 Mar; 75(9):1503-1505. PMID: 36862382
No abstract available.
10.
Hill J, Kiem E, Bhatti A, Liu W, Keane-Candib J, Fitzpatrick K, et al.
Am J Transplant . 2023 Feb; 23(3):416-422. PMID: 36748802
Antibodies against foreign human leukocyte antigen (HLA) molecules are barriers to successful organ transplantation. B cell-depleting treatments are used to reduce anti-HLA antibodies but have limited efficacy. We hypothesized that...