Sean S Davies
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Explore the profile of Sean S Davies including associated specialties, affiliations and a list of published articles.
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91
Citations
3255
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Recent Articles
1.
Fadaei R, Bernstein A, Jenkins A, Pickens A, Zarrow J, Alli-Oluwafuyi A, et al.
bioRxiv
. 2024 Nov;
PMID: 39554116
-acyl phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD) hydrolyzes phosphatidylethanolamines (PE) where the headgroup nitrogen has been enzymatically modified with acyl chains of four carbons or longer (-acyl-PEs or NAPEs). The nitrogen headgroup...
2.
Mashhadi Z, Yin L, Dosoky N, Chen W, Davies S
Prostaglandins Other Lipid Mediat
. 2024 Jul;
174():106869.
PMID: 38977258
Dysregulation of energy balance leading to obesity is a significant risk factor for cardiometabolic diseases such as diabetes, non-alcoholic fatty liver disease and atherosclerosis. In rodents and several other vertebrates,...
3.
Subati T, Yang Z, Murphy M, Stark J, Trykall D, Davies S, et al.
Cells
. 2024 Mar;
13(6.
PMID: 38534327
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, yet the cellular and molecular mechanisms underlying the AF substrate remain unclear. Isolevuglandins (IsoLGs) are highly reactive lipid dicarbonyl products...
4.
Zarrow J, Alli-Oluwafuyi A, Youwakim C, Kim K, Jenkins A, Suero I, et al.
ACS Chem Biol
. 2023 Aug;
18(8):1891-1904.
PMID: 37531659
-Acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) is a zinc metallohydrolase that hydrolyzes -acyl-phosphatidylethanolamines (NAPEs) to form -acyl-ethanolamines (NAEs) and phosphatidic acid. Several lines of evidence suggest that reduced NAPE-PLD activity could...
5.
Davies S, Fessel J, Milne G, Moore K, Yin H
Free Radic Biol Med
. 2023 Jul;
207:45-47.
PMID: 37453234
No abstract available.
6.
Linton M, Yancey P, Tao H, Davies S
Circ Res
. 2023 May;
132(11):1521-1545.
PMID: 37228232
Epidemiologic studies detected an inverse relationship between HDL (high-density lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease (ASCVD), identifying HDL-C as a major risk factor for ASCVD and suggesting atheroprotective...
7.
Zarrow J, Alli-Oluwafuyi A, Youwakim C, Kim K, Jenkins A, Suero I, et al.
bioRxiv
. 2023 Feb;
PMID: 36747693
-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) is a zinc metallohydrolase that hydrolyzes -acyl-phosphatidylethanolamine (NAPEs) to form -acyl-ethanolamides (NAEs) and phosphatidic acid. Several lines of evidence suggest that reduced NAPE-PLD activity could...
8.
Davies S, Forman H
Arch Biochem Biophys
. 2023 Jan;
735:109513.
PMID: 36646268
No abstract available.
9.
Huang J, Tao H, Yancey P, Leuthner Z, May-Zhang L, Jung J, et al.
Mol Metab
. 2022 Dec;
67:101651.
PMID: 36481344
Objective: Oxidative stress contributes to the development of insulin resistance (IR) and atherosclerosis. Peroxidation of lipids produces reactive dicarbonyls such as Isolevuglandins (IsoLG) and malondialdehyde (MDA) that covalently bind plasma/cellular...
10.
Zhong J, Yang H, Shelton E, Matsusaka T, Clark A, Yermalitsky V, et al.
JCI Insight
. 2022 Sep;
7(21).
PMID: 36125905
Lipoprotein modification by reactive dicarbonyls, including isolevuglandin (IsoLG), produces dysfunctional particles. Kidneys participate in lipoprotein metabolism, including tubular uptake. However, the process beyond the proximal tubule is unclear, as is...