Sean P Saunders
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Explore the profile of Sean P Saunders including associated specialties, affiliations and a list of published articles.
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30
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1894
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Recent Articles
1.
Aranda C, Gonzalez-Kozlova E, Saunders S, Fernandes-Braga W, Ota M, Narayanan S, et al.
Allergy
. 2022 Nov;
78(3):752-766.
PMID: 36445014
Background: Atopic diseases are characterized by IgE antibody responses that are dependent on cognate CD4 T cell help and T cell-produced IL-4 and IL-13. Current models of IgE cell differentiation...
2.
Bone R, Fennell B, Tam A, Sheldon R, Nocka K, Varghese S, et al.
Antib Ther
. 2022 Oct;
5(4):258-267.
PMID: 36299415
Background: Interleukin (IL)25 has been implicated in tissue homeostasis at barrier surfaces and the initiation of type two inflammatory signaling in response to infection and cell injury across multiple organs....
3.
Wang Y, Noyer L, Kahlfuss S, Raphael D, Tao A, Kaufmann U, et al.
Sci Adv
. 2022 Oct;
8(40):eabn6552.
PMID: 36206339
T cell activation and function depend on Ca signals mediated by store-operated Ca entry (SOCE) through Ca release-activated Ca (CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE...
4.
Saunders S, Floudas A, Moran T, Byrne C, Rooney M, Fahy C, et al.
Allergy
. 2020 Jul;
75(12):3216-3227.
PMID: 32644214
Background: Atopic dermatitis (AD) is associated with a dysregulation of the skin barrier and may predispose to the development of secondary allergic conditions, such as asthma. Tmem79 mice harbor a...
5.
Saunders S, Ma E, Aranda C, Curotto de Lafaille M
Front Immunol
. 2019 May;
10:715.
PMID: 31105687
The long-term effectiveness of antibody responses relies on the development of humoral immune memory. Humoral immunity is maintained by long-lived plasma cells that secrete antigen-specific antibodies, and memory B cells...
6.
Schwartz C, Moran T, Saunders S, Kaszlikowska A, Floudas A, Bom J, et al.
Allergy
. 2019 Apr;
74(10):1920-1933.
PMID: 30937919
Background: Atopic dermatitis (AD) is one of the most common skin diseases with a multifactorial etiology. Mutations leading to loss of skin barrier function are associated with the development of...
7.
He J, Subramaniam S, Narang V, Srinivasan K, Saunders S, Carbajo D, et al.
Nat Commun
. 2018 Mar;
9(1):968.
PMID: 29497073
The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost labels 'IgE spleen' and 'IgE...
8.
Floudas A, Cluxton C, Fahel J, Khan A, Saunders S, Amu S, et al.
PLoS Negl Trop Dis
. 2017 Oct;
11(10):e0006012.
PMID: 29073139
The helminth Schistosoma mansoni modulates the infected host's immune system to facilitate its own survival, by producing excretory/secretory molecules that interact with a variety of the host's cell types including...
9.
He J, Subramaniam S, Narang V, Srinivasan K, Saunders S, Carbajo D, et al.
Nat Commun
. 2017 Sep;
8(1):641.
PMID: 28935935
The unique differentiation of IgE cells suggests unconventional mechanisms of IgE memory. IgE germinal centre cells are transient, most IgE cells are plasma cells, and high affinity IgE is produced...
10.
Schwartz C, Khan A, Floudas A, Saunders S, Hams E, Rodewald H, et al.
J Exp Med
. 2017 Jul;
214(9):2507-2521.
PMID: 28747424
Group 2 innate lymphoid cells (ILC2s) are important effector cells driving the initiation of type 2 immune responses leading to adaptive T helper 2 (Th2) immunity. Here we show that...