Sean P Saunders
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Explore the profile of Sean P Saunders including associated specialties, affiliations and a list of published articles.
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30
Citations
1894
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Recent Articles
11.
Floudas A, Saunders S, Moran T, Schwartz C, Hams E, Fitzgerald D, et al.
J Immunol
. 2017 Jun;
199(2):707-717.
PMID: 28615416
Atopic dermatitis (AD) is a common inflammatory skin disease affecting up to 20% of children and 3% of adults worldwide and is associated with dysregulation of the skin barrier. Although...
12.
Spence S, Greene M, Fay F, Hams E, Saunders S, Hamid U, et al.
Sci Transl Med
. 2015 Sep;
7(303):303ra140.
PMID: 26333936
Sepsis is the most frequent cause of death in hospitalized patients, and severe sepsis is a leading contributory factor to acute respiratory distress syndrome (ARDS). At present, there is no...
13.
Saunders S, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, et al.
J Allergy Clin Immunol
. 2015 Aug;
137(2):482-91.
PMID: 26299987
Background: Atopic dermatitis (AD) is an inflammatory skin condition that can occur in early life, predisposing to asthma development in a phenomenon known as the atopic march. Although genetic and...
14.
Khan A, Amu S, Saunders S, Hams E, Blackshields G, Leonard M, et al.
Eur J Immunol
. 2015 Mar;
45(6):1842-54.
PMID: 25763771
B cells have been described as having the capacity to regulate cellular immune responses and suppress inflammatory processes. One such regulatory B-cell population is defined as IL-10-producing CD19(+) CD1d(hi) cells....
15.
Khan A, Amu S, Saunders S, Fallon P
Methods Mol Biol
. 2014 Jul;
1190:143-62.
PMID: 25015279
The activation of B cells by pathogens to elicit antibody production is a central facet of immunity. Pathogens also evoke the expansion of B cells that can function in the...
16.
Doyle S, Ozaki E, Brennan K, Humphries M, Mulfaul K, Keaney J, et al.
Sci Transl Med
. 2014 Apr;
6(230):230ra44.
PMID: 24695684
Age-related macular degeneration (AMD) is the most common form of central retinal blindness globally. Distinct processes of the innate immune system, specifically activation of the NLRP3 inflammasome, have been shown...
17.
Hams E, Armstrong M, Barlow J, Saunders S, Schwartz C, Cooke G, et al.
Proc Natl Acad Sci U S A
. 2013 Dec;
111(1):367-72.
PMID: 24344271
Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we...
18.
Salimi M, Barlow J, Saunders S, Xue L, Gutowska-Owsiak D, Wang X, et al.
J Exp Med
. 2013 Dec;
210(13):2939-50.
PMID: 24323357
Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their development. We show that human ILC2s express skin homing receptors and infiltrate the skin after allergen...
19.
Saunders S, Goh C, Brown S, Palmer C, Porter R, Cole C, et al.
J Allergy Clin Immunol
. 2013 Oct;
132(5):1121-9.
PMID: 24084074
Background: Atopic dermatitis (AD) is a major inflammatory condition of the skin caused by inherited skin barrier deficiency, with mutations in the filaggrin gene predisposing to development of AD. Support...
20.
Aviello G, Amu S, Saunders S, Fallon P
Phytother Res
. 2013 Apr;
28(2):300-4.
PMID: 23554071
Inflammatory bowel disease is an urgent public health problem with a high incidence in developed countries. Alterations of lifestyle or dietary interventions may attenuate the disease progression and increase the...